IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens (Q36759545)

16 August 2017

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title

IRG proteins: key mediators of interferon-regulated host resistance to intracellular pathogens (English)

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16 August 2017

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Gregory A Taylor

1

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16 August 2017

13 March 2007

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16 August 2017

Cellular Microbiology

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16 August 2017

9

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16 August 2017

1099-1107

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16 August 2017

5

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The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

16 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

p47 GTPases regulate Toxoplasma gondii survival in activated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Dynamin family of mechanoenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

STAT1 is essential for antimicrobial effector function but dispensable for gamma interferon production during Toxoplasma gondii infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Crystal structure of IIGP1: a paradigm for interferon-inducible p47 resistance GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Interferon action: induction of specific proteins in mouse and human cells by homologous interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Microarray analysis of IFN-gamma response genes in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Regulation of gene expression in RAW 264.7 macrophage cell line by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Dynamin as a mover and pincher during cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Toxoplasmic encephalitis in AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

IFN-inducible GTPases and immunity to intracellular pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

GTPase activity of dynamin and resulting conformation change are essential for endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The interferon-inducible GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Mechanisms regulating the positioning of mouse p47 resistance GTPases LRG-47 and IIGP1 on cellular membranes: retargeting to plasma membrane induced by phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Chlamydial IFN-gamma immune evasion is linked to host infection tropism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The dynamin superfamily: universal membrane tubulation and fission molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Regulating actin dynamics at membranes: a focus on dynamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Dynamin2 and cortactin regulate actin assembly and filament organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Impairment of dynamin's GAP domain stimulates receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Toxoplasma gondii: perfecting an intracellular life style

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Different subcellular localizations for the related interferon-induced GTPases, MuGBP-1 and MuGBP-2: implications for different functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The Ras superfamily at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2007.00916.X

10.1111/J.1462-5822.2007.00916.X

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17359233