Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL) (Q36708664)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23364791%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL) (English)

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23 February 2020

7

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23 February 2020

8

Robert V Farese

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23 February 2020

author name string

Andrew D Nguyen

1

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23 February 2020

Thi A Nguyen

2

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23 February 2020

Basar Cenik

3

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23 February 2020

Gang Yu

4

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23 February 2020

Joachim Herz

5

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23 February 2020

Tobias C Walther

6

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23 February 2020

language of work or name

English

0 references

publication date

30 January 2013

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Journal of Biological Chemistry

23 February 2020

published in

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23 February 2020

volume

288

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23 February 2020

issue

12

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23 February 2020

page(s)

8627-8635

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Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

23 February 2020

cites work

1 reference

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Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration

30 September 2017

1 reference

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The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

30 September 2017

1 reference

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Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

30 September 2017

1 reference

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rs5848 polymorphism and serum progranulin level

30 September 2017

1 reference

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Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging

30 September 2017

1 reference

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HDL/apolipoprotein A-I binds to macrophage-derived progranulin and suppresses its conversion into proinflammatory granulins

30 September 2017

1 reference

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Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

30 September 2017

1 reference

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Progranulin is expressed within motor neurons and promotes neuronal cell survival

30 September 2017

1 reference

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Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members

30 September 2017

1 reference

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Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue

30 September 2017

1 reference

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Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration.

30 September 2017

1 reference

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Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin

30 September 2017

1 reference

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Gene expression study on peripheral blood identifies progranulin mutations

30 September 2017

1 reference

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Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

30 September 2017

1 reference

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Regulation of progranulin expression in myeloid cells

30 September 2017

1 reference

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Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

Progranulin is a mediator of the wound response

30 September 2017

1 reference

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Design and solution structure of a well-folded stack of two beta-hairpins based on the amino-terminal fragment of human granulin A

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

A 30-residue fragment of the carp granulin-1 protein folds into a stack of two beta-hairpins similar to that found in the native protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605681

Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I

30 September 2017

1 reference

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Structure and chromosomal location of the human granulin gene

30 September 2017

1 reference

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Kinetics of lipid-protein interactions: interaction of apolipoprotein A-I from human plasma high density lipoproteins with phosphatidylcholines

30 September 2017

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Proteomic characterization of human plasma high density lipoprotein fractionated by gel filtration chromatography.

30 September 2017

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A solvent system for delipidation of plasma or serum without protein precipitation

28 June 2018

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PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue

28 June 2018

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Progranulin expression in the developing and adult murine brain.

5 September 2018

1 reference

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Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease.

5 September 2018

1 reference

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High-Density Lipoproteins Inhibit Cytokine-Induced Expression of Endothelial Cell Adhesion Molecules

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23364791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Granulins: the structure and function of an emerging family of growth factors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23364791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.441949

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23364791%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

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23 February 2020

PubMed publication ID

23364791

1 reference