Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction (Q36706030)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1448068%20AND%20SRC:MED&resulttype=core&format=json

15 September 2019

title

Hydrolysis of phosphatidylcholine is stimulated by Ras proteins during mitogenic signal transduction (English)

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15 September 2019

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5

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15 September 2019

author name string

H Cai

1

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15 September 2019

P Erhardt

2

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15 September 2019

J Szeberényi

3

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15 September 2019

M T Diaz-Meco

4

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15 September 2019

J Moscat

6

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15 September 2019

G M Cooper

7

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15 September 2019

language of work or name

English

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publication date

1 December 1992

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Molecular and Cellular Biology

15 September 2019

published in

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15 September 2019

volume

12

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15 September 2019

issue

12

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15 September 2019

page(s)

5329-5335

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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

15 September 2019

cites work

1 reference

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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

30 September 2017

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In yeast, RAS proteins are controlling elements of adenylate cyclase.

30 September 2017

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p21H-ras-induced morphological transformation and increases in c-myc expression are independent of functional protein kinase C.

30 September 2017

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Inositol phosphates and cell signalling

30 September 2017

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30 September 2017

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Binding of GAP to activated PDGF receptors

30 September 2017

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Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

30 September 2017

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Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells

30 September 2017

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Signaling through phosphatidylcholine breakdown.

30 September 2017

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Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

30 September 2017

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Cloning and sequencing of the gene encoding the phosphatidylcholine-preferring phospholipase C of Bacillus cereus.

28 June 2018

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Elevated levels of diacylglycerol and decreased phorbol ester sensitivity in ras-transformed fibroblasts

28 June 2018

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Requirement for c-ras proteins during viral oncogene transformation

28 June 2018

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The structure, expression, and properties of additional members of the protein kinase C family.

28 June 2018

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Stimulation of phosphatidylcholine hydrolysis, diacylglycerol release, and arachidonic acid production by oncogenic ras is a consequence of protein kinase C activation

28 June 2018

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PDGF induction of tyrosine phosphorylation of GTPase activating protein

28 June 2018

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Phorbol diesters stimulate the accumulation of phosphatidate, phosphatidylethanol, and diacylglycerol in three cell types. Evidence for the indirect formation of phosphatidylcholine-derived diacylglycerol by a phospholipase D pathway and direct form

28 June 2018

1 reference

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Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.

28 June 2018

1 reference

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Kinetic evidence of a rapid activation of phosphatidylcholine hydrolysis by Ki-ras oncogene. Possible involvement in late steps of the mitogenic cascade

28 June 2018

1 reference

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Differential metabolism of diradyl glycerol molecular subclasses and molecular species by rabbit brain diglyceride kinase.

28 June 2018

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PDGF beta-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

28 June 2018

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Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

28 June 2018

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Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras.

28 June 2018

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Mechanism of inhibition of adenylate cyclase by phospholipase C-catalyzed hydrolysis of phosphatidylcholine. Involvement of a pertussis toxin-sensitive G protein and protein kinase C.

28 June 2018

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Quantitative analysis of molecular species of diacylglycerol and phosphatidate formed upon muscarinic receptor activation of human SK-N-SH neuroblastoma cells

28 June 2018

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Multiple sources of sn-1,2-diacylglycerol in platelet-derived-growth-factor-stimulated Swiss 3T3 fibroblasts. Evidence for activation of phosphoinositidase C and phosphatidylcholine-specific phospholipase D.

28 June 2018

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Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism

28 June 2018

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Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol

28 June 2018

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

28 June 2018

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Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

28 June 2018

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12 December 2020

Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells

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12 December 2020

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

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12 December 2020

Protein kinase C-independent expression of stromelysin by platelet-derived growth factor, ras oncogene, and phosphatidylcholine-hydrolyzing phospholipase C

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12 December 2020

Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic peptide-stimulated human neutrophils. Involvement of phosphatidate phosphohydrolase in signal transduction

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12 December 2020

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

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12 December 2020

Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene

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12 December 2020

Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line

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12 December 2020

Identifiers

DOI

10.1128/MCB.12.12.5329

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1448068%20AND%20SRC:MED&resulttype=core&format=json

15 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1448068%20AND%20SRC:MED&resulttype=core&format=json

15 September 2019

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