The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers (Q36695552)

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1 January 2020

title

The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers (English)

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1 January 2020

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7

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1 January 2020

Adrian Harris

5

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1 January 2020

author name string

J Chakrabarti

1

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1 January 2020

H Turley

2

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1 January 2020

L Campo

3

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1 January 2020

C Han

4

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K C Gatter

6

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1 January 2020

language of work or name

English

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publication date

1 August 2004

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British Journal of Cancer

1 January 2020

published in

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1 January 2020

volume

91

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1 January 2020

page(s)

954-958

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1 January 2020

issue

5

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6602059

1 January 2020

exact match

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cites work

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DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer

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mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression

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DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter

30 September 2017

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DEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities

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Regulation of STRA13 by the von Hippel-Lindau tumor suppressor protein, hypoxia, and the UBC9/ubiquitin proteasome degradation pathway

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Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins

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Hypoxia-inducible expression of tumor-associated carbonic anhydrases

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

5 September 2018

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5 September 2018

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Crossref

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Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen

21 January 2018

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6602059

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15328513%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15328513%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference