A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer. (Q36693026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

main subject

phase I clinical trial

0 references

author

Melodi P. Javid

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Alexander L Lazarides

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Matija Snuderl

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Dan Blazer

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

23

Linda G Griffith

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

21

Rakesh K Jain

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

25

David G Kirsch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

24

Moungi G Bawendi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

20

Dai Fukumura

1 reference

4 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

Diana M Cardona

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Ivan Spasojevic

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Jorge M Ferrer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Joan Cahill

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Chang-Lung Lee

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

E Shelley Hwang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Rachel A Greenup

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Paul J Mosca

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Jeffrey K Mito

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Kyle C Cuneo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Nicole A Larrier

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Erin K O'Reilly

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Richard F Riedel

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

William C Eward

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

David B Strasfeld

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

W David Lee

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Brian E Brigman

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

English

0 references

publication date

1 January 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

4 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

320ra4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

320

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

A Plasmonic Gold Nanostar Theranostic Probe for In Vivo Tumor Imaging and Photothermal Therapy

4 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Detection of intestinal cancer by local, topical application of a quenched fluorescence probe for cysteine cathepsins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Prospective trial with optical molecular imaging for percutaneous interventions in focal hepatic lesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Real-time intraoperative detection of breast cancer using near-infrared fluorescence imaging and Methylene Blue

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

In vivo assessment of HER2 receptor density in HER2-positive tumors by near-infrared imaging, using repeated injections of the fluorescent probe

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Imaging primary mouse sarcomas after radiation therapy using cathepsin-activatable fluorescent imaging agents

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Near infrared fluorescence-guided real-time endoscopic detection of peritoneal ovarian cancer nodules using intravenously injected indocyanine green

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Cysteine cathepsins: multifunctional enzymes in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Molecular imaging in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Distinct role of macrophages in different tumor microenvironments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Accuracy of intraoperative frozen-section analysis of breast cancer lumpectomy-bed margins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Allometric scaling of pharmacokinetic parameters in drug discovery: can human CL, Vss and t1/2 be predicted from in-vivo rat data?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

In vivo molecular target assessment of matrix metalloproteinase inhibition

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Unraveling the role of proteases in cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

In vivo imaging of tumors with protease-activated near-infrared fluorescent probes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Local failure and margin status in early-stage breast carcinoma treated with conservation surgery and radiation therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Power and sample size calculations. A review and computer program

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Allometric scaling of pegylated liposomal anticancer drugs.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Curvature in metabolic scaling.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

A spatially and temporally restricted mouse model of soft tissue sarcoma.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4794335

Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD0293

Analysis of prognostic factors in 1,041 patients with localized soft tissue sarcomas of the extremities

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26738797

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26738797

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.AAD0293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26738797%20AND%20SRC:MED&resulttype=core&format=json