Regulators of G-protein-coupled receptor-G-protein coupling: antidepressants mechanism of action (Q36691772)

15 August 2017

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title

Regulators of G-protein-coupled receptor-G-protein coupling: antidepressants mechanism of action (English)

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G protein-coupled receptor

15 August 2017

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author name string

Gabriel Schreiber

series ordinal

1

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PubMed ID

17187499

15 August 2017

Sofia Avissar

series ordinal

2

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15 August 2017

1 January 2007

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Expert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders

15 August 2017

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15 August 2017

7

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15 August 2017

1

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15 August 2017

75-84

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Chronic exposure of human cells in culture to the tricyclic antidepressant desipramine reduces the number of beta-adrenoceptors.

15 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Effect of the tricyclic antidepressant desipramine on beta-adrenergic receptors in cultured rat glioma C6 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Development of β-adrenergic receptor subsensitivity by antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Expanding the horizons of depression: beyond the monoamine hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

St. John's wort extract Ze 117 (Hypericum perforatum) inhibits norepinephrine and serotonin uptake into rat brain slices and reduces 3-adrenoceptor numbers on cultured rat brain cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

G protein signaling and the molecular basis of antidepressant action

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Ziskind-Somerfeld research Award. The involvement of guanine nucleotide binding proteins in the pathogenesis and treatment of affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Interaction of antibipolar and antidepressant treatments with receptor-coupled G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S]GTP gamma S binding in rat brain regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Chronic fluoxetine treatment selectively uncouples raphe 5-HT(1A) receptors as measured by [(35)S]-GTP gamma S autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

GTP-binding-protein-coupled receptor kinases--two mechanistic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Pathophysiological roles of G-protein-coupled receptor kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Arresting developments in heptahelical receptor signaling and regulation

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Desensitization of G protein-coupled receptors and neuronal functions

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737175.7.1.75

The pharmacology of phosducin

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Interactions of phosducin with defined G protein beta gamma-subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Effects of phosducin on the GTPase cycle of Go.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Regulation of GRK 2 and 6, beta-arrestin-2 and associated proteins in the prefrontal cortex of drug-free and antidepressant drug-treated subjects with major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Acute treatment with the cyclic antidepressant desipramine, but not fluoxetine, increases membrane-associated G protein-coupled receptor kinases 2/3 in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Role of clathrin-mediated endocytosis in agonist-induced down-regulation of the beta2-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

A central role for beta-arrestins and clathrin-coated vesicle-mediated endocytosis in beta2-adrenergic receptor resensitization. Differential regulation of receptor resensitization in two distinct cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Historical review: a brief history and personal retrospective of seven-transmembrane receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Transduction of receptor signals by beta-arrestins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Reduced activation and expression of ERK1/2 MAP kinase in the post-mortem brain of depressed suicide subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

MAP kinase activation by fluoxetine and its relation to gene expression in cultured rat astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Stimulation of immediate early gene expression by desipramine in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Contrasting Fos expression induced by acute reboxetine and fluoxetine in the rat forebrain: neuroanatomical substrates for the antidepressant effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Association and linkage analyses of RGS4 polymorphisms in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

Toward molecular diagnostics of mood disorders in psychiatry

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737175.7.1.75

21 January 2018

Identifiers

DOI

10.1586/14737175.7.1.75

1 reference

15 August 2017

1 reference

PubMed ID

17187499