Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13. (Q36677173)

15 August 2017

Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13. (English)

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15 August 2017

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Von Willebrand factor

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

2

Sriram Krishnaswamy

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15 August 2017

Wenjing Cao

1

1 reference

15 August 2017

Rodney M Camire

series ordinal

3

1 reference

15 August 2017

Peter J Lenting

series ordinal

4

1 reference

15 August 2017

X Long Zheng

series ordinal

5

1 reference

15 August 2017

language of work or name

English

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publication date

20 May 2008

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Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

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15 August 2017

105

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15 August 2017

7416-7421

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15 August 2017

21

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Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Removal of B-domain sequences from factor V rather than specific proteolysis underlies the mechanism by which cofactor function is realized

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

The factor VIII/von Willebrand factor complex: basic and clinical issues.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Deficiency of von Willebrand factor-cleaving protease in familial and acquired thrombotic thrombocytopenic purpura

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

The life cycle of coagulation factor VIII in view of its structure and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Association of the factor VIII light chain with von Willebrand factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Calculation of protein extinction coefficients from amino acid sequence data

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Activation of porcine factor VIII:C by thrombin and factor Xa.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Zinc and calcium ions cooperatively modulate ADAMTS13 activity

28 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801735105

Absence of compensatory platelet activation in patients with severe haemophilia, but evidence for a platelet collagen-activation defect

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801735105

Acquired von Willebrand factor deficiency during high-dose infusion of recombinant factor VIII.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0801735105

Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

Isolation and characterization of thrombin-activated human factor VIII.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396690

von Willebrand factor is a cofactor for thrombin-catalyzed cleavage of the factor VIII light chain

5 September 2018

1 reference

12 December 2020

Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit

1 reference

12 December 2020

Characterization of the interaction between the A2 subunit and A1/A3-C1-C2 dimer in human factor VIIIa

1 reference

12 December 2020

Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease

1 reference

12 December 2020

1 reference

12 December 2020

Stoichiometry of the porcine factor VIII-von Willebrand factor association

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0801735105

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15 August 2017

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15 August 2017

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