A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. (Q36676005)

15 August 2017

21 June 2020

A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. (English)

1 reference

National Institute for Occupational Safety and Health

15 August 2017

1 reference

21 June 2020

1 reference

21 June 2020

acute respiratory distress syndrome

1 reference

Age factors

1 reference

21 June 2020

Age groups

1 reference

21 June 2020

lung disease

1 reference

21 June 2020

Respiratory system disorders

1 reference

21 June 2020

Physiological response

1 reference

21 June 2020

5

David C Christiani

1 reference

15 August 2017

Zhaoxi Wang

1

1 reference

15 August 2017

Douglas Beach

series ordinal

2

1 reference

15 August 2017

Li Su

series ordinal

3

1 reference

15 August 2017

Rihong Zhai

series ordinal

4

1 reference

15 August 2017

language of work or name

English

1 reference

inferred from title

process of elimination

publication date

18 January 2008

1 reference

American Journal of Respiratory Cell and Molecular Biology

15 August 2017

2 references

15 August 2017

21 June 2020

38

1 reference

15 August 2017

6

1 reference

15 August 2017

724-732

1 reference

Harvard T.H. Chan School of Public Health

15 August 2017

performing organization

object named as

Harvard School of Public Health

1 reference

NIOSHTIC-2

on focus list of Wikimedia project

2 February 2024

Wikimedia–NIOSH collaboration

0 references

1 reference

25 September 2023

Microarray-based analysis of ventilator-induced lung injury

1 reference

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Microarray-based identification of novel biomarkers in asthma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Newly recognized causes of acute lung injury: transfusion of blood products, severe acute respiratory syndrome, and avian influenza.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Rat toxicogenomic study reveals analytical consistency across microarray platforms

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Interactions between influenza and bacterial respiratory pathogens: implications for pandemic preparedness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Extracellular thioredoxin levels are increased in patients with acute lung injury.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

SLPI and elafin: one glove, many fingers.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Gene expression profiles distinguish idiopathic pulmonary fibrosis from hypersensitivity pneumonitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Global gene expression profiling in whole-blood samples from individuals exposed to metal fumes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

GeneNotes--a novel information management software for biologists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Analysis of genomic and proteomic data using advanced literature mining

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Gene ontology: tool for the unification of biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Chemokines in lung injury: Thomas A. Neff Lecture

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Studies on the pathogenesis of the adult respiratory distress syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Protein permeability in the adult respiratory distress syndrome. Loss of size selectivity of the alveolar epithelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Role of antileukoprotease in the human lung

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Elastolytic activity in pulmonary lavage fluid from patients with adult respiratory-distress syndrome

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Functional and genomic changes induced by alveolar transmigration in human neutrophils.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Elafin and its precursor trappin-2 still inhibit neutrophil serine proteinases when they are covalently bound to extracellular matrix proteins by tissue transglutaminase

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

-308GA and TNFB polymorphisms in acute respiratory distress syndrome

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Proteolytic susceptibility of the serine protease inhibitor trappin-2 (pre-elafin): evidence for tryptase-mediated generation of elafin.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Clinical features and outcomes of severe acute respiratory syndrome and predictive factors for acute respiratory distress syndrome

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Alveolar granulocyte colony-stimulating factor and alpha-chemokines in relation to serum levels, pulmonary neutrophilia, and severity of lung injury in ARDS.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Polymorphism in the surfactant protein-B gene, gender, and the risk of direct pulmonary injury and ARDS.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Analysis of high density expression microarrays with signed-rank call algorithms.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2396250

Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance

20 September 2018

1 reference

12 December 2020

Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups

1 reference

12 December 2020

Elastase inhibitor elafin is a new type of proteinase inhibitor which has a transglutaminase-mediated anchoring sequence termed "cementoin"

1 reference

12 December 2020

SKALP/elafin is an inducible proteinase inhibitor in human epidermal keratinocytes

1 reference

12 December 2020

Levels of skin-derived antileukoproteinase (SKALP)/elafin in serum correlate with disease activity during treatment of severe psoriasis with cyclosporin A

1 reference

12 December 2020

Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome

1 reference

12 December 2020

Elafin/elastase-specific inhibitor in bronchoalveolar lavage of normal subjects and farmer's lung

1 reference

12 December 2020

Sustained high levels of circulatory interleukin-8 are associated with a poor outcome in patients with adult respiratory distress syndrome

1 reference

12 December 2020

Neutrophil apoptosis in the acute respiratory distress syndrome

1 reference

12 December 2020

Role of interleukin 8 in the genesis of acute respiratory distress syndrome through an effect on neutrophil apoptosis

1 reference

12 December 2020

Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome

1 reference

12 December 2020

Collagenase in the lower respiratory tract of patients with adult respiratory distress syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1165/RCMB.2007-0354OC

1 reference

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

18203972

1 reference