The role of airway secretions in COPD: pathophysiology, epidemiology and pharmacotherapeutic options (Q36674100)

15 August 2017

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title

The role of airway secretions in COPD: pathophysiology, epidemiology and pharmacotherapeutic options (English)

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chronic obstructive pulmonary disease

15 August 2017

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1 reference

Duncan F Rogers

1

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PubMed ID

17146999

15 August 2017

language of work or name

English

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publication date

1 September 2005

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COPD: Journal of Chronic Obstructive Pulmonary Disease

15 August 2017

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15 August 2017

2

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15 August 2017

3

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15 August 2017

341-353

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The natural history of chronic airflow obstruction

15 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Definitions of emphysema, chronic bronchitis, asthma, and airflow obstruction: 25 years on from the Ciba symposium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Pathophysiology of airflow limitation in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Chronic mucus hypersecretion in COPD and death from pulmonary infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Mucus clearance as a primary innate defense mechanism for mammalian airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

21 January 2018

The airway goblet cell

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Physiology and pathology of tracheobronchial glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

The MUC family: an obituary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

MUC17, a novel membrane-tethered mucin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Structural organization and classification of the human mucin genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Isolation and characterization of the major form of human MUC18 cDNA gene and correlation of MUC18 over-expression in prostate cancer cell lines and tissues with malignant progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Genome-wide search and identification of a novel gel-forming mucin MUC19/Muc19 in glandular tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Molecular Cloning, Genomic Structure, and Expression Analysis of MUC20, a Novel Mucin Protein, Up-regulated in Injured Kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Comparison of the structural and inflammatory features of COPD and asthma. Giles F. Filley Lecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Mediators of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Morphometric analysis of intraluminal mucus in airways in chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Use of mucin antibodies and cDNA probes to quantify hypersecretion in vivo in human airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Structure of central airways in current smokers and ex-smokers with and without mucus hypersecretion: relationship to lung function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Measurement of the bronchial mucous gland layer: a diagnostic yardstick in chronic bronchitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

The size of the bronchial glands in chronic bronchitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Distribution of bronchial gland measurements in a Jamaican population

21 January 2018

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https://api.crossref.org/works/10.1080%2F15412550500218098

A DISTRIBUTION CURVE FOR CHRONIC BRONCHITIS.

21 January 2018

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https://api.crossref.org/works/10.1080%2F15412550500218098

Mucins in airway secretions from healthy and chronic bronchitic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Respiratory mucins: identification of core proteins and glycoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

MUC5B is a major gel-forming, oligomeric mucin from human salivary gland, respiratory tract and endocervix: identification of glycoforms and C-terminal cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Expression of respiratory mucins in fatal status asthmaticus and mild asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Expression of MUC5AC and MUC5B mucins in normal and cystic fibrosis lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Mucociliary clearance in the airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Relationship between bronchial reversibility and tracheobronchial clearance in patients with chronic bronchitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Effect of forced expirations on mucus clearance in patients with chronic airflow obstruction: effect of lung recoil pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Twelve Years Spirometric Changes Among Paris Area Workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Respiratory symptoms and pulmonary function as predictors of 10-year mortality from respiratory disease, cardiovascular disease, and all causes in the Whitehall Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Relevance of airflow obstruction and mucus hypersecretion to mortality

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Site and Nature of Airway Obstruction in Chronic Obstructive Lung Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Respiratory symptoms, lung function, and mortality in a screening center cohort.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

The value of mucus hypersecretion as a predictor of mortality and hospitalization. An 11-year register based follow-up study of a random population sample of 876 men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Factors associated with increased risk of exacerbation and hospital admission in a cohort of ambulatory COPD patients: a multiple logistic regression analysis. The EOLO Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Mucociliary dysfunction in COPD: effect of current pharmacotherapeutic options

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Airway goblet cells: responsive and adaptable front-line defenders

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Evaluation of current pharmacotherapy of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Mucoactive drugs for asthma and COPD: any place in therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

The effect of oral N-acetylcysteine in chronic bronchitis: a quantitative systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Oxidative stress and lung inflammation in airways disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Inhibition of human neutrophil elastase by erythromycin and flurythromycin, two macrolide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Therapy for chronic obstructive pulmonary disease in the 21st century.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Bax is crucial for IFN-gamma-induced resolution of allergen-induced mucus cell metaplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Oblimersen sodium (Genasense bcl-2 antisense oligonucleotide): a rational therapeutic to enhance apoptosis in therapy of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Clinical studies with non-iressa EGFR tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Oxygen metabolites stimulate release of high-molecular-weight glycoconjugates by cell and organ cultures of rodent respiratory epithelium via an arachidonic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Motor control of airway goblet cells and glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Pharmacological regulation of the neuronal control of airway mucus secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

The vanilloid receptor: a molecular gateway to the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Epoxygenase pathways of arachidonic acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Clinical and cellular effects of cytochrome P-450 modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Application of expression microarrays to the investigation of fetal lung development in a glucocorticoid receptor knockout mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Expression of ErbB receptors and mucins in the airways of long term current smokers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Lung mucin production is stimulated by the air pollutant residual oil fly ash

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Suplatast tosilate inhibits goblet-cell metaplasia of airway epithelium in sensitized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Novel cytoplasmic proteins of nontypeable Haemophilus influenzae up-regulate human MUC5AC mucin transcription via a positive p38 mitogen-activated protein kinase pathway and a negative phosphoinositide 3-kinase-Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Regulation of the secretory phenotype of human airway epithelium by retinoic acid, triiodothyronine, and extracellular matrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

P2Y(2) receptor agonists: a new class of medication targeted at improved mucociliary clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

ATP induced MUC5AC release from human airways in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Airway goblet-cell mucus secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

A Calcium-Activated Chloride Channel Blocker Inhibits Goblet Cell Metaplasia and Mucus Overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

Chronic obstructive pulmonary disease mortality in six U.S. cities

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15412550500218098

10.1080/15412550500218098

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference

PubMed ID

17146999