Wnts as ligands: processing, secretion and reception (Q36672661)

15 August 2017

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title

Wnts as ligands: processing, secretion and reception (English)

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15 August 2017

Mikels AJ

1

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15 August 2017

Nusse R

series ordinal

2

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15 August 2017

language of work or name

English

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publication date

1 December 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

57

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15 August 2017

7461-7468

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210053

15 August 2017

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cites work

Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A new member of the frizzled family from Drosophila functions as a Wingless receptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A dedicated Wnt secretion factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

EphB/EphrinB receptors and Wnt signaling in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt gradient formation requires retromer function in Wnt-producing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

WNT/Frizzled signaling in eye development and disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The Ror receptor tyrosine kinase family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

WNT signaling in malignant mesothelioma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Argosomes: a potential vehicle for the spread of morphogens through epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A new secreted protein that binds to Wnt proteins and inhibits their activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Biochemical characterization of Wnt-frizzled interactions using a soluble, biologically active vertebrate Wnt protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Trimeric G protein-dependent frizzled signaling in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Interaction of Wnt-1 proteins with the binding protein BiP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Regulation of bone mass by Wnt signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

LRP5/6 in Wnt signaling and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

NMR structure of the WIF domain of the human Wnt-inhibitory factor-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Developmental roles of heparan sulfate proteoglycans in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The Wnt signaling pathway in development and disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Mutational analysis of mouse Wnt-1 identifies two temperature-sensitive alleles and attributes of Wnt-1 protein essential for transformation of a mammary cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Differential requirements for segment polarity genes in wingless signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

dishevelled and armadillo act in the wingless signalling pathway in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

1 reference

7 January 2021

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Lipoprotein particles are required for Hedgehog and Wingless signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt signalling in stem cells and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Components of wingless signalling in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Lipid rafts and signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt-frizzled signaling to G-protein-coupled effectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt proteins are lipid-modified and can act as stem cell growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Ligand receptor interactions in the Wnt signaling pathway in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

The Frizzled CRD domain is conserved in diverse proteins including several receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Expression and function of the Ror-family receptor tyrosine kinases during development: lessons from genetic analyses of nematodes, mice, and humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Wnt-mediated axon guidance via the Drosophila Derailed receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Direct and long-range action of a wingless morphogen gradient

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210053

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210053

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Dimensions Publication ID

15 August 2017

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1 reference