Type 1 angiotensin receptor pharmacology: signaling beyond G proteins. (Q36663074)

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22 December 2019

review article

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title

Type 1 angiotensin receptor pharmacology: signaling beyond G proteins (English)

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22 December 2019

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2

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22 December 2019

author name string

Cristina Oro

series ordinal

1

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22 December 2019

Walter G Thomas

series ordinal

3

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22 December 2019

publication date

14 October 2006

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Pharmacology & Therapeutics

22 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17125841%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

113

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22 December 2019

issue

1

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22 December 2019

page(s)

210-226

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Mechanisms and functions of AT(1) angiotensin receptor internalization

22 December 2019

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Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

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Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

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Structural determinants for the activation mechanism of the angiotensin II type 1 receptor differ for phosphoinositide hydrolysis and mitogen-activated protein kinase pathways

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Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.

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Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro

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Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways

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Visualization of dynamic trafficking of a protein kinase C betaII/green fluorescent protein conjugate reveals differences in G protein-coupled receptor activation and desensitization

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Identification of structural determinants for G protein-independent activation of mitogen-activated protein kinases in the seventh transmembrane domain of the angiotensin II type 1 receptor

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beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

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Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes

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Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness

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Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II.

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Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2.

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12 December 2020

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Genetic polymorphisms and heart failure

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12 December 2020

Hypertension as a complex genetic trait

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12 December 2020

N-glycosylation requirements for the AT1a angiotensin II receptor delivery to the plasma membrane

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12 December 2020

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12 December 2020

When 7 transmembrane receptors are not G protein-coupled receptors

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12 December 2020

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Alternative splicing: a novel mechanism to fine-tune the expression and function of the human AT1 receptor

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12 December 2020