BMP signaling in the cartilage growth plate. (Q36659526)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

review article

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title

BMP signaling in the cartilage growth plate (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

Karen Lyons

series ordinal

2

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22 December 2019

publication date

1 January 2006

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Current Topics in Developmental Biology

22 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

76

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22 December 2019

page(s)

1-48

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Fibroblast growth factor inhibits chondrocytic growth through induction of p21 and subsequent inactivation of cyclin E-Cdk2

22 December 2019

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Coordinated expression of noggin and bone morphogenetic proteins (BMPs) during early skeletogenesis and induction of noggin expression by BMP-7.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Noggin inhibits chondrogenic but not osteogenic differentiation in mesodermal stem cell line C1 and skeletal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Smad2 role in mesoderm formation, left-right patterning and craniofacial development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Growth factor regulation of human growth plate chondrocyte proliferation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

CD44 modulates Smad1 activation in the BMP-7 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Mutations in CDMP1 cause autosomal dominant brachydactyly type C

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Transforming growth factor-beta 3 is required for secondary palate fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Molecular mechanisms of endochondral bone development.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Transforming growth factor (TGF)-beta-activated kinase 1 mimics and mediates TGF-beta-induced stimulation of type II collagen synthesis in chondrocytes independent of Col2a1 transcription and Smad3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Differential effects of ERK and p38 signaling in BMP-2 stimulated hypertrophy of cultured chick sternal chondrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Regulation of the chondrocyte phenotype by beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

DRAGON, a bone morphogenetic protein co-receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Filamin associates with Smads and regulates transforming growth factor-beta signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Joint development in Xenopus laevis and induction of segmentations in regenerating froglet limb (spike).

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Brachydactyly type C caused by a homozygous missense mutation in the prodomain of CDMP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Delivery of bone morphogenetic proteins for orthopedic tissue regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Activating and deactivating mutations in the receptor interaction site of GDF5 cause symphalangism or brachydactyly type A2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Indian hedgehog gene is a target of the bone morphogenetic protein signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

TGF-beta signaling in human skeletal and patterning disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Parathyroid hormone-related peptide (PTHrP)-dependent and -independent effects of transforming growth factor beta (TGF-beta) on endochondral bone formation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Distinct roles of Smad pathways and p38 pathways in cartilage-specific gene expression in synovial fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Requirement of autocrine signaling by bone morphogenetic protein-4 for chondrogenic differentiation of ATDC5 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

The transcription factors L-Sox5 and Sox6 are essential for cartilage formation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

GDF5 coordinates bone and joint formation during digit development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Developmental failure of phalanges in the absence of growth/differentiation factor 5

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

A human chondrodysplasia due to a mutation in a TGF-beta superfamily member

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Functions of transforming growth factor-beta family type I receptors and Smad proteins in the hypertrophic maturation and osteoblastic differentiation of chondrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Chondroprotective drugs in degenerative joint diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

A BMP responsive transcriptional region in the chicken type X collagen gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

FGFs, their receptors, and human limb malformations: clinical and molecular correlations

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Differential growth by growth plates as a function of multiple parameters of chondrocytic kinetics.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Ectopic induction of tendon and ligament in rats by growth and differentiation factors 5, 6, and 7, members of the TGF-beta gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Bone morphogenetic proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Novel regulators of bone formation: molecular clones and activities

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

C-type natriuretic peptide enhances osteogenic protein-1-induced osteoblastic cell differentiation via Smad5 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

The type I BMP receptor BmprIB is essential for female reproductive function

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Multiple functions of BMPs in chondrogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

The transcription factor Sox9 is involved in BMP-2 signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

A role for the BMP antagonist chordin in endochondral ossification.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Smad4 is required for the normal organization of the cartilage growth plate

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte-specific expression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

A new role for BMP5 during limb development acting through the synergic activation of Smad and MAPK pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2806%2976001-X

7 January 2021

10.1016/S0070-2153(06)76001-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17118262%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference