8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation (Q36653805)

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scientific article published on 4 February 2013

Language	Label	Description	Also known as
English	8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation	scientific article published on 4 February 2013

Statements

scholarly article

1 reference

Europe PubMed Central

15 August 2017

8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation (English)

1 reference

Europe PubMed Central

15 August 2017

8-(4-chlorophenylthio)-cAMP

1 reference

ChEBI release 2020-05-28

acute promyelocytic leukemia

1 reference

based on heuristic

inferred from title

cell differentiation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

12

object named as

Hugues de Thé

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7

object named as

Julien Ablain

1 reference

Europe PubMed Central

15 August 2017

author name string

Bo Jiao

1

1 reference

Europe PubMed Central

15 August 2017

Zhi-Hong Ren

2

1 reference

Europe PubMed Central

15 August 2017

Ping Liu

3

1 reference

Europe PubMed Central

15 August 2017

Li-Juan Chen

4

1 reference

Europe PubMed Central

15 August 2017

Jing-Yi Shi

5

1 reference

Europe PubMed Central

15 August 2017

Ying Dong

6

1 reference

Europe PubMed Central

15 August 2017

Lin Shi

8

1 reference

Europe PubMed Central

15 August 2017

Li Gao

9

1 reference

Europe PubMed Central

15 August 2017

Jun-Pei Hu

10

1 reference

Europe PubMed Central

15 August 2017

Rui-Bao Ren

11

1 reference

Europe PubMed Central

15 August 2017

Zhu Chen

13

1 reference

Europe PubMed Central

15 August 2017

Sai-Juan Chen

14

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

4 February 2013

1 reference

Europe PubMed Central

15 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

15 August 2017

110

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Europe PubMed Central

15 August 2017

3495-3500

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Europe PubMed Central

15 August 2017

9

1 reference

Europe PubMed Central

15 August 2017

Revisiting the differentiation paradigm in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Acute promyelocytic leukemia: from highly fatal to highly curable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Phosphorylation by PKA potentiates retinoic acid receptor alpha activity by means of increasing interaction with and phosphorylation by cyclin H/cdk7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Adaptive immunity cooperates with liposomal all-trans-retinoic acid (ATRA) to facilitate long-term molecular remissions in mice with acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Translocations of the RARalpha gene in acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Two critical hits for promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Distinct leukemia phenotypes in transgenic mice and different corepressor interactions generated by promyelocytic leukemia variant fusion genes PLZF-RARalpha and NPM-RARalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

PML/RAR alpha+ U937 mutant and NB4 cell lines: retinoic acid restores the monocytic differentiation response to vitamin D3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

30 September 2017

PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

28 June 2018

The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

28 June 2018

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

28 June 2018

Complete remission through blast cell differentiation in PLZF/RARalpha-positive acute promyelocytic leukemia: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

Anti-proliferative effects of 8-chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase A-mediated desubordination of retinoid X receptor

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M. D. Anderson Cancer Center Series.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

hCG-PLZF-RARalpha/hCG-RARalpha-PLZF transgenic mice developing into leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

20 September 2018

Synergic effects of arsenic trioxide and cAMP during acute promyelocytic leukemia cell maturation subtends a novel signaling cross-talk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3587232

20 September 2018

Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222863110

21 January 2018

Complete remission of t(11;17) positive acute promyelocytic leukemia induced by all-trans retinoic acid and granulocyte colony-stimulating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23382200

12 December 2020

based on heuristic

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Identifiers

10.1073/PNAS.1222863110

1 reference

Europe PubMed Central

15 August 2017

2013PNAS..110.3495J

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1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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