'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer (Q36643808)

15 August 2017

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title

'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer (English)

1 reference

15 August 2017

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Mark Berneburg

1

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15 August 2017

York Kamenisch

series ordinal

2

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15 August 2017

Jean Krutmann

series ordinal

3

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15 August 2017

Martin Röcken

series ordinal

4

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15 August 2017

1 December 2006

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15 August 2017

Experimental Dermatology

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15 August 2017

15

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15 August 2017

12

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15 August 2017

1005-1015

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15 August 2017

Oxidative Decay of DNA

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial Oxidative Stress and Mitochondrial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Repair of mtDNA in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidative DNA damage: mechanisms, mutation, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mutagenesis by 8-oxoguanine: an enemy within

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial reactive oxygen species generation and calcium increase induced by visible light in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondria-derived reactive oxygen species mediate blue light-induced death of retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Femtosecond near-infrared laser pulses elicit generation of reactive oxygen species in mammalian cells leading to apoptosis-like death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Activation of molecular oxygen by infrared laser radiation in pigment-free aerobic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Topology of superoxide production from different sites in the mitochondrial electron transport chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Intracellular generation of reactive oxygen species by mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidative damage and mitochondrial decay in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidative damage to mitochondrial DNA and its relationship to ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

21 January 2018

Photoaging of human skin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Human skin mitochondrial DNA deletions associated with light exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Singlet oxygen mediates the UVA-induced generation of the photoaging-associated mitochondrial common deletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Stereoselective excision of thymine glycol from oxidatively damaged DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Efficient repair of abasic sites in DNA by mitochondrial enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA ligase III function is independent of Xrcc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mismatch repair activity in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Nuclear and mitochondrial DNA repair: similar pathways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The life and death of DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Regulation and mechanisms of mammalian double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mammalian mitochondria possess homologous DNA recombination activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Tissue dependent co-segregation of the novel pathogenic G12276A mitochondrial tRNALeu(CUN) mutation with the A185G D-loop polymorphism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Recombination of mitochondrial DNA in skeletal muscle of individuals with multiple mitochondrial DNA heteroplasmy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mammalian mitochondrial extracts possess DNA end-binding activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Cockayne syndrome group B cellular and biochemical functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Transcription-coupled repair of 8-oxoguanine: requirement for XPG, TFIIH, and CSB and implications for Cockayne syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Genetically determined conidial longevity is positively correlated with superoxide dismutase, catalase, glutathione peroxidase, cytochrome c peroxidase, and ascorbate free radical reductase activities in Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Influences of aging and dietary restriction on serum thymosin alpha 1 levels in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Does oxidative damage to DNA increase with age?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Exogenous insulin can reverse the effects of caloric restriction on mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidative aging and insulin receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

There is substantial agreement among interspecies estimates of DNA repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Premature aging in mice deficient in DNA repair and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial repair of 8-oxoguanine and changes with aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mechanism of telomere shortening by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Photoaging of the skin from phenotype to mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Induction of the photoaging-associated mitochondrial common deletion in vivo in normal human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Molecular basis of sun-induced premature skin ageing and retinoid antagonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

On the Origin of Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The pathophysiology of mitochondrial cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial defects in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Pathways of apoptotic and non-apoptotic death in tumour cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Apoptosis induced by ultraviolet B in HPV-immortalized human keratinocytes requires caspase-9 and is death receptor independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Overcoming Fas-mediated apoptosis accelerates Helicobacter-induced gastric cancer in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondria-to-nucleus stress signaling induces phenotypic changes, tumor progression and cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Estrogen-induced mitochondrial reactive oxygen species as signal-transducing messengers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial impairment is accompanied by impaired oxidative DNA repair in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Reactive oxygen species derived from the mitochondrial respiratory chain are not responsible for the basal levels of oxidative base modifications observed in nuclear DNA of Mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Oxidized guanine lesions and hOgg1 activity in lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Somatic mutations of the mitochondrial genome in human colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA damage in non-melanoma skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA alterations in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Large germline deletions of mitochondrial complex II subunits SDHB and SDHD in hereditary paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA 4,977-bp deletion in paired oral cancer and precancerous lesions revealed by laser microdissection and real-time quantitative PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Superoxide dismutase evolution and life span regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2006.00508.X

10.1111/J.1600-0625.2006.00508.X

21 January 2018

Identifiers

DOI

1 reference

15 August 2017

1 reference