Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance. (Q36634268)

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scientific article published on 17 August 2011

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English	Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.	scientific article published on 17 August 2011

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scholarly article

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11 February 2020

Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance (English)

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11 February 2020

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11 February 2020

author name string

Kamal K Balavenkatraman

1

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11 February 2020

Adrian Britschgi

3

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11 February 2020

Urs Mueller

4

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11 February 2020

Benjamin G Neel

6

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11 February 2020

Mohamed Bentires-Alj

7

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11 February 2020

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publication date

17 August 2011

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11 February 2020

Molecular Cancer Research

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11 February 2020

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10

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11 February 2020

1377-1384

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Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis

1 reference

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30 September 2017

Protein-tyrosine phosphatases and cancer

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The role of protein tyrosine phosphatase 1B in Ras signaling

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Protein tyrosine phosphatase 1B attenuates growth hormone-mediated JAK2-STAT signaling

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Regulation of insulin-like growth factor type I (IGF-I) receptor kinase activity by protein tyrosine phosphatase 1B (PTP-1B) and enhanced IGF-I-mediated suppression of apoptosis and motility in PTP-1B-deficient fibroblasts

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Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

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Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

1 reference

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30 September 2017

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

1 reference

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Transformation suppression by protein tyrosine phosphatase 1B requires a functional SH3 ligand

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Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer.

1 reference

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28 June 2018

Effect of protein tyrosine phosphatase 1B expression on transformation by the human neu oncogene

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Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells

1 reference

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Neuronal PTP1B regulates body weight, adiposity and leptin action.

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Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression

1 reference

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12 December 2020

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Insulin and related factors in premenopausal breast cancer risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/21849469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights from transgenic mouse models of ERBB2-induced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21849469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1541-7786.MCR-11-0198

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11 February 2020

1 reference

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11 February 2020

1 reference

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11 February 2020

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