The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway (Q36623825)

15 August 2017

The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway (English)

1 reference

15 August 2017

traumatic brain injury

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author name string

Tao Chen

1

1 reference

15 August 2017

Lei Zhang

2

1 reference

15 August 2017

Yan Qu

3

1 reference

15 August 2017

Kai Huo

4

1 reference

15 August 2017

Xiaofan Jiang

5

1 reference

15 August 2017

Zhou Fei

6

1 reference

15 August 2017

28 December 2011

1 reference

International Journal of Molecular Medicine

15 August 2017

1 reference

15 August 2017

29

1 reference

15 August 2017

4

1 reference

15 August 2017

630-636

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3577346/fullTextXML

inferred from PubMed Central ID database lookup

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30 September 2017

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Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma

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mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors

30 September 2017

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

30 September 2017

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Regulation of cell death protease caspase-9 by phosphorylation

30 September 2017

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Factors affecting excitatory amino acid release following severe human head injury

30 September 2017

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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28 June 2018

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28 June 2018

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Severity of controlled cortical impact traumatic brain injury in rats and mice dictates degree of behavioral deficits.

20 September 2018

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20 September 2018

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The inhibition of glycogen synthase kinase 3beta by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Abeta peptides

20 September 2018

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20 September 2018

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A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons.

20 September 2018

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Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

20 September 2018

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Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.

20 September 2018

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MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor

20 September 2018

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20 September 2018

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20 September 2018

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Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription.

20 September 2018

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Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage.

20 September 2018

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Talampanel, a novel noncompetitive AMPA antagonist, is neuroprotective after traumatic brain injury in rats

20 September 2018

1 reference

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Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum

20 September 2018

1 reference

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Group I metabotropic glutamate antagonist reduces acute neuronal degeneration and behavioral deficits after traumatic brain injury in rats.

20 September 2018

1 reference

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Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury.

20 September 2018

1 reference

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Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events

20 September 2018

1 reference

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(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

20 September 2018

1 reference

12 December 2020

Traumatic brain injury

1 reference

12 December 2020

The role of excitatory amino acids and NMDA receptors in traumatic brain injury

1 reference

12 December 2020

Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide

1 reference

12 December 2020

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain

1 reference

12 December 2020

Identifiers

DOI

10.3892/IJMM.2011.870

1 reference

15 August 2017

1 reference

15 August 2017

1 reference