Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9 (Q36618530)

15 August 2017

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9 (English)

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15 August 2017

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11 June 2020

Nicola Santoro

2

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11 June 2020

author name string

Yonglin Chen

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11 June 2020

Rafaz Hoque

4

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11 June 2020

Xinshou Ouyang

5

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11 June 2020

Mark J Shlomchik

7

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11 June 2020

Robert Lee Coffman

8

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11 June 2020

Albert Candia

9

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11 June 2020

Wajahat Zafar Mehal

10

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11 June 2020

Sonia Caprio

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11 June 2020

language of work or name

English

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publication date

25 January 2016

1 reference

Journal of Clinical Investigation

15 August 2017

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11 June 2020

volume

126

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11 June 2020

issue

3

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11 June 2020

page(s)

859-864

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Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

NAFLD in 2014: Genetics, diagnostics and therapeutic advances in NAFLD.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Circulating mitochondrial DAMPs cause inflammatory responses to injury

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4767345

Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26808498

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12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI83885

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26808498%20AND%20SRC:MED&resulttype=core&format=json

release_kep7s4mvtrg5dgzutxak3yll3i

11 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/kep7s4mvtrg5dgzutxak3yll3i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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11 June 2020

1 reference

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