Mutations in Rb1 pathway-related genes are associated with poor prognosis in anaplastic astrocytomas. (Q36614860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15970925%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Mutations in Rb1 pathway-related genes are associated with poor prognosis in anaplastic astrocytomas (English)

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13 January 2020

1

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13 January 2020

author name string

B R Nilsson

2

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13 January 2020

L Liu

3

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13 January 2020

K Ichimura

4

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13 January 2020

V P Collins

5

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13 January 2020

language of work or name

English

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publication date

1 July 2005

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British Journal of Cancer

13 January 2020

published in

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13 January 2020

volume

93

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13 January 2020

issue

1

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13 January 2020

page(s)

124-130

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6602661

13 January 2020

exact match

0 references

cites work

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

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The conditional probabilities of survival in patients with anaplastic astrocytoma or glioblastoma multiforme

30 September 2017

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Haplo-insufficiency? Let me count the ways

30 September 2017

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Postoperative radiotherapy of astrocytomas

30 September 2017

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A Generalized Two-Sample Wilcoxon Test for Doubly Censored Data

30 September 2017

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Multiple deleted regions on the long arm of chromosome 6 in astrocytic tumours

30 September 2017

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Investigation of genetic alterations associated with the grade of astrocytic tumor by comparative genomic hybridization

28 June 2018

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Gene amplification as a prognostic factor in primary brain tumors.

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Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

28 June 2018

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Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities.

28 June 2018

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Genetic pathways to glioblastoma: a population-based study

27 July 2018

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Short postoperative survival for glioblastoma patients with a dysfunctional Rb1 pathway in combination with no wild-type PTEN.

20 September 2018

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Molecular markers of prognosis in astrocytic tumors.

20 September 2018

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PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme.

20 September 2018

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The complexity of the 7p12 amplicon in human astrocytic gliomas: detailed mapping of 246 tumors.

20 September 2018

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Functional evaluation of p53 and PTEN gene mutations in gliomas.

20 September 2018

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Mutational profile of the PTEN gene in primary human astrocytic tumors and cultivated xenografts.

20 September 2018

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Clinicopathologic study of 85 similarly treated patients with anaplastic astrocytic tumors. An analysis of DNA content (ploidy), cellular proliferation, and p53 expression.

20 September 2018

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Gene amplification as a prognostic factor in primary and secondary high-grade malignant gliomas.

20 September 2018

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Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades.

20 September 2018

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Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group.

20 September 2018

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PTEN gene mutations are seen in high-grade but not in low-grade gliomas.

20 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361485

Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361485

CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated.

20 September 2018

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Alterations of the TP53 gene in human gliomas.

20 September 2018

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CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

20 September 2018

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20 September 2018

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Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15970925

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6602661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15970925%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15970925%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference