Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies (Q36608759)

15 August 2017

Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies (English)

1 reference

15 August 2017

Sharma R

1

1 reference

15 August 2017

Kacevska M

2

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15 August 2017

London R

3

1 reference

15 August 2017

Clarke SJ

4

1 reference

15 August 2017

Liddle C

5

1 reference

15 August 2017

Robertson G

6

1 reference

15 August 2017

language of work or name

English

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publication date

4 December 2007

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British Journal of Cancer

15 August 2017

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15 August 2017

98

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15 August 2017

1

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15 August 2017

91-97

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6604101

15 August 2017

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Is nuclear factor kappa-B the missing link between inflammation, cancer and alteration in hepatic drug metabolism in patients with cancer?

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Regulation of drug-metabolizing enzymes and transporters in inflammation

30 September 2017

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Systemic inflammatory response predicts outcome in patients undergoing resection for ductal adenocarcinoma head of pancreas.

30 September 2017

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The complexities of hepatic drug transport: current knowledge and emerging concepts.

30 September 2017

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Lessons from the CYP3A4 promoter

30 September 2017

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Enterohepatic bile salt transporters in normal physiology and liver disease

30 September 2017

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Inflammatory response: an unrecognised source of variability in the pharmacokinetics and pharmacodynamics of cancer chemotherapy

30 September 2017

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The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

30 September 2017

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Hepatic cytochrome P450 3A drug metabolism is reduced in cancer patients who have an acute-phase response

30 September 2017

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Overexpression of IL-6 but not IL-8 increases paclitaxel resistance of U-2OS human osteosarcoma cells

30 September 2017

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The role of C-reactive protein as a prognostic indicator in advanced cancer

30 September 2017

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Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells.

30 September 2017

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Regulation of cytochrome p450 by inflammatory mediators: why and how?

30 September 2017

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Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis

30 September 2017

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The role of cytokines in both the normal and malignant ovary

30 September 2017

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In vitro and in vivo drug interactions involving human CYP3A.

30 September 2017

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Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism

30 September 2017

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Role of interleukin-1 in the depression of liver drug metabolism by endotoxin

30 September 2017

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Molecular biology of P-glycoprotein

30 September 2017

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Regulation of cytochromes P450 during inflammation and infection.

30 September 2017

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Recombinant tumor necrosis factor depresses cytochrome P450-dependent microsomal drug metabolism in mice.

28 June 2018

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Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer.

28 June 2018

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Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

20 September 2018

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The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice

20 September 2018

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Involvement of interleukin-6 and tumor necrosis factor alpha in CYP3A11 and 2C29 down-regulation by Bacillus Calmette-Guerin and lipopolysaccharide in mouse liver

20 September 2018

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Hepatic expression of multiple acute phase proteins and down-regulation of nuclear receptors after acute endotoxin exposure.

20 September 2018

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Toxic rise of clozapine plasma concentrations in relation to inflammation

20 September 2018

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Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

20 September 2018

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Nuclear Receptors Orchestrate Detoxification Pathways

20 September 2018

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Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure

20 September 2018

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Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure

20 September 2018

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Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia.

20 September 2018

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Influence of IL-6 on MDR and MRP-mediated multidrug resistance in human hepatoma cells.

20 September 2018

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Decreased expression of P-glycoprotein in interleukin-1beta and interleukin-6 treated rat hepatocytes.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359691

Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359691

Effects of glucocorticoids on pharmacokinetics and pharmacodynamics of midazolam in rats.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359691

Production and effects of interleukin-6 and other cytokines in patients with non-Hodgkin's lymphoma.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359691

Endogenous interleukin 6 is a resistance factor for cis-diamminedichloroplatinum and etoposide-mediated cytotoxicity of human prostate carcinoma cell lines.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359691

Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent

20 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6604101

Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats

21 January 2018

1 reference

12 December 2020

Acute-phase response, interleukin-6, and alteration of cyclosporine pharmacokinetics

1 reference

12 December 2020

Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture

1 reference

12 December 2020

Oncostatin M down-regulates basal and induced cytochromes P450 in human hepatocytes

1 reference

12 December 2020

Systemic inflammatory response, prostate-specific antigen and survival in patients with metastatic prostate cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6604101

1 reference

15 August 2017

1 reference

15 August 2017

1 reference