The genetics of systemic lupus erythematosus: understanding how SNPs confer disease susceptibility (Q36590524)

15 August 2017

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title

The genetics of systemic lupus erythematosus: understanding how SNPs confer disease susceptibility (English)

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systemic lupus erythematosus

15 August 2017

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Marta E Alarcón-Riquelme

series ordinal

1

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15 August 2017

9 September 2006

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Seminars in Immunopathology

15 August 2017

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15 August 2017

28

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15 August 2017

2

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15 August 2017

109-117

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https://scigraph.springernature.com/pub.10.1007/s00281-006-0033-4

15 August 2017

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cites work

Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes

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https://api.crossref.org/works/10.1007%2FS00281-006-0033-4

Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00281-006-0033-4

Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00281-006-0033-4

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

21 January 2018

1 reference

12 December 2020

Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope

1 reference

12 December 2020

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

1 reference

12 December 2020

HapMap: Building a Database with Blocks

1 reference

12 December 2020

Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

1 reference

12 December 2020

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

1 reference

12 December 2020

Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice

1 reference

12 December 2020

The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia

1 reference

12 December 2020

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

12 December 2020

The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis

1 reference

12 December 2020

Structural variants: changing the landscape of chromosomes and design of disease studies

1 reference

12 December 2020

Polygenic control of susceptibility to murine systemic lupus erythematosus

1 reference

12 December 2020

The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression

1 reference

12 December 2020

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

1 reference

12 December 2020

Perspectives on human genetic variation from the HapMap Project.

1 reference

12 December 2020

The natural interferon-alpha producing cells in systemic lupus erythematosus

1 reference

12 December 2020

The R620W C/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1.

1 reference

12 December 2020

A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families

1 reference

12 December 2020

Genetic Contributions to Lupus‐like Disease in (NZB×NZW)F1 Mice

1 reference

12 December 2020

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

1 reference

12 December 2020

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

1 reference

12 December 2020

Protein tyrosine phosphatase gene (PTPN22) polymorphism in multiple sclerosis.

1 reference

12 December 2020

Fine Mapping of the SLEB2 Locus Involved in Susceptibility to Systemic Lupus Erythematosus

1 reference

12 December 2020

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

1 reference

12 December 2020

Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes

1 reference

12 December 2020

PD-1 ligands, negative regulators for activation of naive, memory, and recently activated human CD4+ T cells.

1 reference

12 December 2020

Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis

1 reference

12 December 2020

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

1 reference

12 December 2020

A haplotype map of the human genome

1 reference

12 December 2020

Power tools for human genetics.

1 reference

12 December 2020

Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases

1 reference

12 December 2020

Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex

1 reference

12 December 2020

Coordinate overexpression of interferon-alpha-induced genes in systemic lupus erythematosus

1 reference

12 December 2020

Identification of novel CBFA1/RUNX2 mutations causing cleidocranial dysplasia

1 reference

12 December 2020

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

1 reference

12 December 2020

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

1 reference

12 December 2020

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

1 reference

12 December 2020

Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus

1 reference

12 December 2020

Upstream and downstream targets of RUNX proteins.

1 reference

12 December 2020

SLC22A4 and RUNX1: identification of RA susceptible genes

1 reference

12 December 2020

Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE)

1 reference

12 December 2020

Facilitation of beta selection and modification of positive selection in the thymus of PD-1-deficient mice

1 reference

12 December 2020

Association of a programmed death 1 gene polymorphism with the development of rheumatoid arthritis, but not systemic lupus erythematosus

1 reference

12 December 2020

Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease

1 reference

12 December 2020

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

1 reference

12 December 2020

Lupus-like disease and high interferon levels corresponding to trisomy of the type I interferon cluster on chromosome 9p

1 reference

12 December 2020

The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms

1 reference

12 December 2020

Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation

1 reference

12 December 2020

Role of an intronic polymorphism in the PDCD1 gene with the risk of sporadic systemic lupus erythematosus and the occurrence of antiphospholipid antibodies

1 reference

12 December 2020

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

1 reference

12 December 2020

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

1 reference

12 December 2020

Mapping common regulatory variants to human haplotypes

1 reference

12 December 2020

The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease

1 reference

12 December 2020

Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus

1 reference

12 December 2020

Influence of human genome polymorphism on gene expression

1 reference

12 December 2020

Genome-wide associations of gene expression variation in humans

1 reference

12 December 2020

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

1 reference

12 December 2020

Population stratification and spurious allelic association

1 reference

12 December 2020

Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

1 reference

12 December 2020

Gaining insight into PTPN22 and autoimmunity

1 reference

12 December 2020

Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.

1 reference

12 December 2020

Isolation and characterization of runxa and runxb, zebrafish members of the runt family of transcriptional regulators

1 reference

12 December 2020

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

12 December 2020

An etiopathogenic role for the type I IFN system in SLE.

1 reference

12 December 2020

A putative regulatory polymorphism in PD-1 is associated with nephropathy in a population-based cohort of systemic lupus erythematosus patients

1 reference

12 December 2020

Mapping determinants of human gene expression by regional and genome-wide association

1 reference

12 December 2020

Runx3 regulates mouse TGF-beta-mediated dendritic cell function and its absence results in airway inflammation

1 reference

12 December 2020

Multiple lupus susceptibility loci map to chromosome 1 in BXSB mice

1 reference

12 December 2020

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

12 December 2020

Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes

1 reference

12 December 2020

Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus

1 reference

12 December 2020

Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees

1 reference

12 December 2020

Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study

1 reference

12 December 2020

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

12 December 2020

Combinatorial interactions of Serpent, Lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis

1 reference

12 December 2020

Structure and chromosomal localization of the human PD-1 gene (PDCD1)

1 reference

12 December 2020

Use of unlinked genetic markers to detect population stratification in association studies.

1 reference

12 December 2020

Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus

1 reference

12 December 2020

Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function

1 reference

12 December 2020

Runt domain factor (Runx)-dependent effects on CCAAT/ enhancer-binding protein delta expression and activity in osteoblasts

1 reference

12 December 2020

Overlapping BXSB congenic intervals, in combination with microarray gene expression, reveal novel lupus candidate genes

1 reference

12 December 2020

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

1 reference

12 December 2020

Lupus susceptibility loci in New Zealand mice

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12 December 2020

The genetics of systemic lupus erythematosus

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12 December 2020

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

1 reference

12 December 2020

Association study designs for complex diseases

1 reference

12 December 2020

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

1 reference

12 December 2020

A RUNX trio with a taste for autoimmunity

1 reference

12 December 2020

A new haplotype of PDCD1 is associated with rheumatoid arthritis in Hong Kong Chinese.

1 reference

12 December 2020

A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families

1 reference

12 December 2020

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes

1 reference

12 December 2020

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

1 reference

12 December 2020

A Susceptibility Locus for Human Systemic Lupus Erythematosus (hSLE1) on Chromosome 2q

1 reference

12 December 2020

Microarray analysis of interferon-regulated genes in SLE.

1 reference

12 December 2020

A genome-wide search for human type 1 diabetes susceptibility genes

1 reference

12 December 2020

A PD-1 polymorphism is associated with disease progression in multiple sclerosis.

1 reference

12 December 2020

Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families

1 reference

12 December 2020

Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes

1 reference

12 December 2020

Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins

1 reference

12 December 2020

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

1 reference

12 December 2020

Association of PDCD1 with susceptibility to systemic lupus erythematosus

1 reference

12 December 2020

An evaluation of HapMap sample size and tagging SNP performance in large-scale empirical and simulated data sets

1 reference

12 December 2020

Decreased production of and response to interleukin-2 by cultured lymphocytes from patients with systemic lupus erythematosus

1 reference

12 December 2020

Smad-Runx interactions during chondrocyte maturation

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12 December 2020

Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease

1 reference

12 December 2020

Case-control studies of association in structured or admixed populations.

1 reference

12 December 2020

10.1007/S00281-006-0033-4

Identifiers

DOI

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15 August 2017

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PubMed ID

16964481