Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo (Q36587730)

15 August 2017

Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo (English)

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15 August 2017

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Dana E Orange

1

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15 August 2017

Nathalie E Blachere

2

1 reference

15 August 2017

John Fak

3

1 reference

15 August 2017

Salina Parveen

4

1 reference

15 August 2017

Mayu O Frank

5

1 reference

15 August 2017

Margo Herre

6

1 reference

15 August 2017

Suyan Tian

7

1 reference

15 August 2017

Sebastien Monette

8

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15 August 2017

Robert B Darnell

9

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15 August 2017

language of work or name

English

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publication date

5 February 2013

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15 August 2017

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15 August 2017

2

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15 August 2017

e00105

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Directing dendritic cell immunotherapy towards successful cancer treatment

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Dendritic cells: emerging pharmacological targets of immunosuppressive drugs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

FK506 markedly enhances apoptosis of antigen-stimulated peripheral T cells by down-regulation of Bcl-xL

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Species differences in sensitivity of T lymphocytes to immunosuppressive effects of FK 506

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Cyclosporin A markedly enhances superantigen-induced peripheral T cell deletion and inhibits anergy induction

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Animal models of arthritis: relevance to human disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Radiologic analysis of arthritis in rats after systemic injection of streptococcal cell walls

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Tacrolimus-induced apoptosis and its prevention by interleukins in mitogen-activated human peripheral-blood mononuclear cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Quantitative and temporal analysis of the cellular interaction of FK-506 and rapamycin in T-lymphocytes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3564474

Immunosuppressive agents mediate reduced allostimulatory properties of myeloid-derived dendritic cells despite induction of divergent molecular phenotypes

28 June 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Isolation of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

FK506 augments activation-induced programmed cell death of T lymphocytes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Tacrolimus and cyclosporine A inhibit allostimulatory capacity and cytokine production of human myeloid dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.00105

Effects of FK506 on exocrine pancreas in rats

21 January 2018

1 reference

12 December 2020

Protective effects of gabexate mesilate on acute pancreatitis induced by tacrolimus (FK-506) in rats in which the pancreas was stimulated by caerulein

1 reference

12 December 2020

FK506 potentiates steroid-induced T-cell apoptosis

1 reference

12 December 2020

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance

1 reference

12 December 2020

Collagen-induced arthritis

1 reference

12 December 2020

The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells

1 reference

12 December 2020

Effective antigen cross-presentation by prostate cancer patients' dendritic cells: implications for prostate cancer immunotherapy

1 reference

12 December 2020

Effects of FK-506 on collagen arthritis in mice

1 reference

12 December 2020

FK-506, a potent novel immunosuppressive agent, binds to a cytosolic protein which is distinct from the cyclosporin A-binding protein, cyclophilin

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.00105

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

23390586

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