Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist (Q36573189)

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scientific article published on 30 November 2012

Language	Label	Description	Also known as
English	Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist	scientific article published on 30 November 2012

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scholarly article

1 reference

Europe PubMed Central

15 August 2017

Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist (English)

1 reference

Europe PubMed Central

15 August 2017

experimental autoimmune encephalomyelitis

1 reference

based on heuristic

inferred from title

author name string

Stuart M Cahalan

1

1 reference

Europe PubMed Central

15 August 2017

Pedro J Gonzalez-Cabrera

2

1 reference

Europe PubMed Central

15 August 2017

Nhan Nguyen

3

1 reference

Europe PubMed Central

15 August 2017

Miguel Guerrero

4

1 reference

Europe PubMed Central

15 August 2017

Elizabeth A George Cisar

5

1 reference

Europe PubMed Central

15 August 2017

Nora B Leaf

6

1 reference

Europe PubMed Central

15 August 2017

Steven J Brown

7

1 reference

Europe PubMed Central

15 August 2017

Edward Roberts

8

1 reference

Europe PubMed Central

15 August 2017

Hugh Rosen

9

1 reference

Europe PubMed Central

15 August 2017

publication date

30 November 2012

1 reference

Europe PubMed Central

15 August 2017

Molecular Pharmacology

1 reference

Europe PubMed Central

15 August 2017

83

1 reference

Europe PubMed Central

15 August 2017

2

1 reference

Europe PubMed Central

15 August 2017

316-321

1 reference

Europe PubMed Central

15 August 2017

An oral sphingosine 1-phosphate receptor 1 (S1P(1)) antagonist prodrug with efficacy in vivo: discovery, synthesis, and evaluation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Crystal structure of a lipid G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

S1P(1) receptor modulation with cyclical recovery from lymphopenia ameliorates mouse model of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Sphingosine 1-phosphate (S1P): Physiology and the effects of S1P receptor modulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

FTY720 modulates human oligodendrocyte progenitor process extension and survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

30 September 2017

A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

28 June 2018

Mapping pathways downstream of sphingosine 1-phosphate subtype 1 by differential chemical perturbation and proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

28 June 2018

Amelioration of collagen-induced arthritis by a novel S1P1 antagonist with immunomodulatory activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

CD69 down-modulation and inhibition of thymic egress by short- and long-term selective chemical agonism of sphingosine 1-phosphate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558813

21 September 2018

The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23204443

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.112.082958

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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