The rise of PAMPA. (Q36572610)

15 August 2017

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title

The rise of PAMPA. (English)

1 reference

15 August 2017

Alex Avdeef

1

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PubMed ID

16922646

15 August 2017

language of work or name

English

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publication date

1 August 2005

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Expert Opinion on Drug Metabolism & Toxicology

15 August 2017

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15 August 2017

1

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15 August 2017

325-342

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15 August 2017

2

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Absorption potential: estimating the fraction absorbed for orally administered compounds

15 August 2017

1 reference

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A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

21 January 2018

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Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio.

21 January 2018

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Guidance in the setting of drug particle size specifications to minimize variability in absorption.

21 January 2018

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Passive diffusion of weak organic electrolytes across Caco-2 cell monolayers: uncoupling the contributions of hydrodynamic, transcellular, and paracellular barriers.

21 January 2018

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Drug absorption in vitro model: filter-immobilized artificial membranes. 2. Studies of the permeability properties of lactones in Piper methysticum Forst

21 January 2018

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Optimized conditions of bio-mimetic artificial membrane permeation assay

21 January 2018

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High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes

21 January 2018

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Molecular properties that influence the oral bioavailability of drug candidates

21 January 2018

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High throughput artificial membrane permeability assay for blood-brain barrier.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.2.325

Prediction of human intestinal permeability using artificial membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

In vitro permeability of poorly aqueous soluble compounds using different solubilizers in the PAMPA assay with liquid chromatography/mass spectrometry detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

PAMPA--a drug absorption in vitro model 8. Apparent filter porosity and the unstirred water layer

21 January 2018

1 reference

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Permeability through DOPC/dodecane membranes: measurement and LFER modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

21 January 2018

1 reference

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Acid-base cosolvent method for determining aqueous permeability of amiodarone, itraconazole, tamoxifen, terfenadine and other very insoluble molecules

21 January 2018

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Comparison of in vitro models for the prediction of compound absorption across the human intestinal mucosa

21 January 2018

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Ionization, lipophilicity, and molecular modeling to investigate permeability and other biological properties of amlodipine

21 January 2018

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Probing the mechanism of drug/lipid membrane interactions using Biacore

21 January 2018

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Contribution of the paracellular route to the pH-dependent epithelial permeability to cationic drugs

21 January 2018

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Exploring the role of different drug transport routes in permeability screening.

21 January 2018

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Physicochemical profiling (solubility, permeability and charge state).

21 January 2018

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High throughput physicochemical profiling for drug discovery

21 January 2018

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Multivariate pharmaceutical profiling for drug discovery

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Improvement of "hit-to-lead" optimization by integration of in vitro HTS experimental models for early determination of pharmacokinetic properties

21 January 2018

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Pharmaceutical profiling in drug discovery.

21 January 2018

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Profiling drug-like properties in discovery research

21 January 2018

1 reference

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In vitro trans-monolayer permeability calculations: often forgotten assumptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

Physicochemical profiling in drug research: a brief survey of the state-of-the-art of experimental techniques

21 January 2018

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Diffusion of Weak Acids across Lipid Bilayer Membranes: Effects of Chemical Reactions in the Unstirred Layers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.2.325

Weak acid transport across bilayer lipid membrane in the presence of buffers. Theoretical and experimental pH profiles in the unstirred layers

21 January 2018

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Diffusion of ionizable solutes across planar lipid bilayer membranes: boundary-layer pH gradients and the effect of buffers.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.1.2.325

Human intestinal permeability

21 January 2018

1 reference

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Application of hydrogen bonding calculations in property based drug design.

21 January 2018

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Classification analysis of P-glycoprotein substrate specificity.

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21 January 2018

Identifiers

DOI

10.1517/17425255.1.2.325

1 reference

15 August 2017

1 reference

PubMed ID

16922646