Relationship between elevated immunoglobulin free light chain and the presence of IgH translocations in multiple myeloma (Q36572310)

15 August 2017

Relationship between elevated immunoglobulin free light chain and the presence of IgH translocations in multiple myeloma (English)

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15 August 2017

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10

R A Kyle

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15 August 2017

13

S V Rajkumar

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15 August 2017

3

A Dispenzieri

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15 August 2017

R Fonseca

14

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author name string

S Kumar

1

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15 August 2017

L Zhang

2

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15 August 2017

S Van Wier

4

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15 August 2017

J A Katzmann

5

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15 August 2017

M Snyder

6

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15 August 2017

E Blood

7

1 reference

15 August 2017

R DeGoey

8

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15 August 2017

K Henderson

9

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15 August 2017

A R Bradwell

11

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15 August 2017

P R Greipp

12

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15 August 2017

3 June 2010

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15 August 2017

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15 August 2017

24

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15 August 2017

1498-1505

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15 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/leu.2010.128

15 August 2017

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cites work

Appraisal of immunoglobulin free light chain as a marker of response

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Role of genetics in prognostication in myeloma

30 September 2017

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Genetic events in the pathogenesis of multiple myeloma

30 September 2017

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Immunoglobulin free light chain ratio is an independent risk factor for progression of smoldering (asymptomatic) multiple myeloma

30 September 2017

1 reference

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Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.

30 September 2017

1 reference

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High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis

30 September 2017

1 reference

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Prognostic value of serum free light chain ratio at diagnosis in multiple myeloma

30 September 2017

1 reference

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Competence and competition: the challenge of becoming a long-lived plasma cell

30 September 2017

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Immunoglobulin free light chains and solitary plasmacytoma of bone

30 September 2017

1 reference

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Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation

30 September 2017

1 reference

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Molecular pathogenesis and a consequent classification of multiple myeloma

30 September 2017

1 reference

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Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy

30 September 2017

1 reference

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International staging system for multiple myeloma

30 September 2017

1 reference

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Diagnostic performance of quantitative kappa and lambda free light chain assays in clinical practice

30 September 2017

1 reference

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Regulation of plasma-cell development

30 September 2017

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30 September 2017

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Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.

30 September 2017

1 reference

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The generation of antibody diversity through somatic hypermutation and class switch recombination

30 September 2017

1 reference

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Review of 1027 patients with newly diagnosed multiple myeloma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

Highly sensitive, automated immunoassay for immunoglobulin free light chains in serum and urine.

30 September 2017

1 reference

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Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma

30 September 2017

1 reference

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Ig light chains are secreted predominantly as monomers

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

Immunoglobulin heavy chain toxicity in plasma cells is neutralized by fusion to pre-B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

A mouse myeloma variant with a defect in light chain synthesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

Coordination of immunoglobulin chain folding and immunoglobulin chain assembly is essential for the formation of functional IgG.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

A possible mechanism of inability of immunoglobulin heavy-chain production in Bence-Jones type myeloma cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

Induction of syngeneic cytotoxic T lymphocytes against a B cell tumor. II. Characterization of anti-idiotypic CTL lines and clones

28 June 2018

1 reference

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Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome.

28 June 2018

1 reference

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Genetics and cytogenetics of multiple myeloma: a workshop report.

21 September 2018

1 reference

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Clinical and biologic implications of recurrent genomic aberrations in myeloma

21 September 2018

1 reference

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Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in multiple myeloma: early results of total therapy II.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3558529

The addition of interferon or high dose cyclophosphamide to standard chemotherapy in the treatment of patients with multiple myeloma: phase III Eastern Cooperative Oncology Group Clinical Trial EST 9486.

21 September 2018

1 reference

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Exon skipping without splice site mutation accounting for abnormal immunoglobulin chains in nonsecretory human myeloma.

21 September 2018

1 reference

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The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2010.128

Analysis of genetic abnormalities provides insights into genetic evolution of hyperdiploid myeloma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2010.128

Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation

21 January 2018

1 reference

12 December 2020

T cell repertoire in patients with multiple myeloma and monoclonal gammopathy of undetermined significance: clonal CD8+ T cell expansions are found preferentially in patients with a low tumor burden

1 reference

12 December 2020

Presence of monoclonal free light chains in the serum predicts risk of progression in monoclonal gammopathy of undetermined significance.

1 reference

12 December 2020

Molecular features responsible for the absence of immunoglobulin heavy chain protein synthesis in an IgH(-) subgroup of multiple myeloma

1 reference

12 December 2020

Biological and prognostic significance of interphase fluorescence in situ hybridization detection of chromosome 13 abnormalities (delta13) in multiple myeloma: an eastern cooperative oncology group study

1 reference

12 December 2020

Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation

1 reference

12 December 2020

Light-chain only multiple myeloma is due to the absence of functional (productive) rearrangement of the IgH gene at the DNA level

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2010.128

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference

15 August 2017

1 reference