Loss of LARGE2 disrupts functional glycosylation of α-dystroglycan in prostate cancer. (Q36561917)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23223448%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Loss of LARGE2 disrupts functional glycosylation of α-dystroglycan in prostate cancer (English)

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20 February 2020

1 reference

1 reference

7

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20 February 2020

Michael D. Henry

11

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20 February 2020

author name string

Alison K Esser

1

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20 February 2020

Michael R Miller

2

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20 February 2020

Qin Huang

3

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20 February 2020

Melissa M Meier

4

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20 February 2020

Daniel Beltran-Valero de Bernabé

5

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20 February 2020

Christopher S Stipp

6

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20 February 2020

Charles F Lynch

8

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20 February 2020

Brian J Smith

9

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20 February 2020

Michael B Cohen

10

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20 February 2020

language of work or name

English

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publication date

6 December 2012

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20 February 2020

number of pages

11

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Journal of Biological Chemistry

inferred from page(s)

published in

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20 February 2020

volume

288

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20 February 2020

issue

4

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20 February 2020

page(s)

2132-2142

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Fer kinase regulates cell migration through α-dystroglycan glycosylation

20 February 2020

cites work

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30 September 2017

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Like-acetylglucosaminyltransferase (LARGE)-dependent modification of dystroglycan at Thr-317/319 is required for laminin binding and arenavirus infection.

30 September 2017

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Reduced glycosylation of α-dystroglycans on carcinoma cells contributes to formation of highly infiltrative histological patterns in prostate cancer

30 September 2017

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Dystroglycan does not contribute significantly to kidney development or function, in health or after injury

30 September 2017

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ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells

30 September 2017

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Dystroglycan is not required for maintenance of the luminal epithelial basement membrane or cell polarity in the mouse prostate.

30 September 2017

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O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.

30 September 2017

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Increments of alpha-dystroglycan expression in liver metastasis correlate with poor survival in gastric cancer.

30 September 2017

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Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase

30 September 2017

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Loss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE.

30 September 2017

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ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells

30 September 2017

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RETRACTED: Dystroglycan and perlecan provide a basal cue required for epithelial polarity during energetic stress

30 September 2017

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Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy

30 September 2017

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Altered expression of natively glycosylated alpha dystroglycan in pediatric solid tumors

30 September 2017

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Dystroglycan expression is reduced during prostate tumorigenesis and is regulated by androgens in prostate cancer cells

30 September 2017

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Dystroglycan loss disrupts polarity and beta-casein induction in mammary epithelial cells by perturbing laminin anchoring.

30 September 2017

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Altered expression of alpha-dystroglycan subunit in human gliomas

30 September 2017

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Dystroglycan: a multifunctional adaptor protein

30 September 2017

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Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function

30 September 2017

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The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma

30 September 2017

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Characterization of the LARGE family of putative glycosyltransferases associated with dystroglycanopathies

30 September 2017

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LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE

30 September 2017

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Proteolytic enzymes and altered glycosylation modulate dystroglycan function in carcinoma cells.

30 September 2017

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Molecular recognition by LARGE is essential for expression of functional dystroglycan

30 September 2017

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Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity

30 September 2017

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Dystroglycan expression is frequently reduced in human breast and colon cancers and is associated with tumor progression.

30 September 2017

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A role for dystroglycan in epithelial polarization: loss of function in breast tumor cells.

30 September 2017

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Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy

30 September 2017

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Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1

30 September 2017

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Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin alpha2 deficiency and abnormal glycosylation of alpha-dystroglycan

30 September 2017

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Selective deficiency of alpha-dystroglycan in Fukuyama-type congenital muscular dystrophy

30 September 2017

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Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse

30 September 2017

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A new mathematical model for relative quantification in real-time RT-PCR

30 September 2017

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Cloning of the human cDNA which can complement the defect of the yeast mannosyltransferase I-deficient mutant alg 1

30 September 2017

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An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy

30 September 2017

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A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin.

30 September 2017

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Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization

30 September 2017

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Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor

30 September 2017

1 reference

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Non-muscle alpha-dystroglycan is involved in epithelial development

30 September 2017

1 reference

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Membrane organization of the dystrophin-glycoprotein complex

30 September 2017

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Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

30 September 2017

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Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila.

30 September 2017

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Post-translational disruption of dystroglycan-ligand interactions in congenital muscular dystrophies

28 June 2018

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Reduced α-dystroglycan expression correlates with shortened patient survival in pancreatic cancer.

28 June 2018

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Aberrant expression of beta-dystroglycan may be due to processing by matrix metalloproteinases-2 and -9 in oral squamous cell carcinoma.

21 September 2018

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Increased expression of dystroglycan inhibits the growth and tumorigenicity of human mammary epithelial cells.

21 September 2018

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LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies.

21 September 2018

1 reference

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Mutations in the FKRP gene can cause muscle-eye-brain disease and Walker-Warburg syndrome.

21 September 2018

1 reference

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A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering

21 September 2018

1 reference

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Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.432807

The fukutin protein family--predicted enzymes modifying cell-surface molecules

21 January 2018

1 reference

12 December 2020

Reduced expression of dystroglycan in breast and prostate cancer

1 reference

12 December 2020

Prediction of prognosis for prostatic adenocarcinoma by combined histological grading and clinical staging

1 reference

12 December 2020

Identification and purification of an agrin receptor from Torpedo postsynaptic membranes: a heteromeric complex related to the dystroglycans

1 reference

12 December 2020

Aberrant expression of alpha-dystroglycan in cervical and vulvar cancer

1 reference

12 December 2020

Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma

1 reference

12 December 2020

Expression of alpha-dystroglycan correlates with tumour grade and predicts survival in oral squamous cell carcinoma

1 reference

12 December 2020

Dystroglycan is associated with tumor progression and patient survival in gastric cancer

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.432807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23223448%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23223448%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23223448%20AND%20SRC:MED&resulttype=core&format=json