The role of redox-active metals in the mechanism of action of bleomycin (Q36561899)

14 August 2017

1 reference

title

The role of redox-active metals in the mechanism of action of bleomycin (English)

1 reference

14 August 2017

D. H. Petering

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1690086

30 October 2022

R. W. Byrnes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1690086

30 October 2022

W. E. Antholine

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1690086

30 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1690086

30 October 2022

publication date

1 January 1990

1 reference

full work available at URL

14 August 2017

https://api.elsevier.com/content/article/PII:0009279790900014?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

https://api.elsevier.com/content/article/PII:0009279790900014?httpAccept=text/plain

30 October 2022

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Chemico-biological Interactions

30 October 2022

published in

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14 August 2017

73

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14 August 2017

2-3

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14 August 2017

133-182

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Biological studies on individual bleomycins.

14 August 2017

1

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Action of bleomycin on DNA and RNA

30 October 2022

3

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Release of free bases from deoxyribonucleic acid after reaction with bleomycin

30 October 2022

4

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Increased DNA chain breakage by combined action of bleomycin and superoxide radical

30 October 2022

6

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

A role for ferrous ion and oxygen in the degradation of DNA by bleomycin

30 October 2022

7

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Effect of chelating agents and metal ions on the degradation of DNA by bleomycin

30 October 2022

8

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Properties and products of the degradation of DNA by bleomycin and iron(II)

30 October 2022

9

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Sequence specific cleavage of DNA by the antitumor antibiotics neocarzinostatin and bleomycin

30 October 2022

10

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

A spectroscopic investigation of the metal binding site of bleomycin A2. The Cu(II) and Zn(II) derivatives

30 October 2022

11

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interactions of bleomycin with DNA

30 October 2022

17

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Mechanism of bleomycin action: studies

30 October 2022

20

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin—mode of action with particular reference to the cell cycle

30 October 2022

24

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

A comparison of the effect of metal-bleomycin complexes on the DNA damage and survival of cultured mammalian cells

30 October 2022

29

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Cobalt-bleomycins and deoxyribonucleic acid: sequence-dependent interactions, action spectrum for nicking, and indifference to oxygen

30 October 2022

30

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Nucleotide sequence cleavages of manganese-bleomycin induced by reductant, hydrogen peroxide and ultraviolet light. Comparison with iron- and cobalt-bleomycins

30 October 2022

31

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Copper-dependent cleavage of DNA by bleomycin

30 October 2022

33

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Activity and toxicity of bleomycin

30 October 2022

34

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Cytotoxic and antitumor properties of bleomycin and several of its metal complexes

30 October 2022

35

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Mechanism of action of bleomycin. Studies with the growing culture of bacterial and tumor cells

30 October 2022

37

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Breaks and rejoining of DNA in cultured mammalian cells treated with bleomycin

30 October 2022

39

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Studies on the chemical reactivity of copper bleomycin

30 October 2022

41

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The combined effects of bleomycin and sulfhydryl compounds on the thermal denaturation of DNA

30 October 2022

43

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

ESR Parameters for Cupric Bleomycin in the Mobilized State

30 October 2022

47

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Transition-metal binding site of bleomycin A2. A carbon-13 nuclear magnetic resonance study of the zinc(II) and copper(II) derivatives

30 October 2022

48

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Proton nuclear magnetic resonance study of the structure of bleomycin and the zinc-bleomycin complex

30 October 2022

49

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Metal binding to modified bleomycins. Zinc and ferrous complexes with an acetylated bleomycin

30 October 2022

50

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Carbon-13 N.M.R. study of bleomycin-A2 protonation

30 October 2022

52

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Conformational flexibility of bleomycin-A2: A carbon-13 spin-lattice relaxation time study

30 October 2022

53

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Proton NMR studies of ternary complexes of bleomycin with metal ions and nucleic acid

30 October 2022

54

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Copper(I)-bleomycin: structurally unique complex that mediates oxidative DNA strand scission

30 October 2022

58

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Location of iron in the Fe2+-bleomycin complex as observed by 13C NMR spectroscopy

30 October 2022

60

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The iron complexes of bleomycin and tallysomycin

30 October 2022

61

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Proton NMR study of iron(II)-bleomycin: assignment of resonances by saturation transfer experiments

30 October 2022

62

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Chemistry of bleomycin. XXII. Interaction of bleomycin with nucleic acids, preferential binding to guanine base and electrostatic effect of the terminal amine

30 October 2022

65

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Studies of metallobleomycins by electronic spectroscopy, electron spin resonance spectroscopy, and potentiometric titration

30 October 2022

68

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Reactions of 3-ethoxy-2-oxobutyraldehyde bis(N4-dimethylthiosemicarbazonato)-zinc(II) with tumor cells and mitochondria

30 October 2022

74

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Metal coordination core of bleomycin: Comparison of metal complexes between bleomycin and its biosynthetic intermediate

30 October 2022

75

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

ESR of copper and iron complexes with antitumor and cytotoxic properties

30 October 2022

77

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

On the reaction of iron bleomycin with thiols and oxygen

30 October 2022

79

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Redox potential of iron-bleomycin

30 October 2022

81

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Spectroscopic studies on bleomycin-iron complexes with carbon monoxide, nitric oxide, isocyanide, azide, and cyanide and comparison with iron-porphyrin complexes

30 October 2022

82

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Reaction of FeB1m with DNA: Fe(II)B1m-NO

30 October 2022

84

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Stimulation of iron(II) bleomycin activity by phosphate-containing compounds

30 October 2022

87

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Oxygen binding to cobalt(II)-bleomycin

30 October 2022

88

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Cobalt-bleomycin-deoxyribonucleic acid system. Evidence of deoxyribonucleic acid bound superoxo and mu-peroxo cobalt-bleomycin complexes

30 October 2022

90

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Identification of a key structural feature of cobalt(III)-bleomycins: An exogenous ligand (e.g. Hydroperoxide) bound to cobalt

30 October 2022

91

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Activity of bleomycin in iron- and copper-deficient cells

30 October 2022

92

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Cobalt chelate of bleomycin. I. Physicochemical properties and distribution in tumor bearing mice

30 October 2022

96

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin may be activated for DNA cleavage by NADPH-cytochrome P-450 reductase

30 October 2022

97

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Copper-bleomycin has no significant DNA cleavage activity

30 October 2022

98

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Photolability of bleomycin and its complexes

30 October 2022

99

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Light-induced nicking of deoxyribonucleic acid by cobalt(III) bleomycins

30 October 2022

100

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

On the mechanism of hydrogen peroxide-, superoxide-, and ultraviolet light-induced DNA cleavages of inactive bleomycin-iron(III) complex

30 October 2022

101

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Free radicals from the photodecomposition of bleomycin

30 October 2022

102

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Photo-induced nicking of deoxyribonucleic acid by ruthenium(II)-bleomycin in the presence of air.

30 October 2022

103

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Electrochemical and ESR studies on Cu(II) complexes of bleomycin and its related compounds

30 October 2022

105

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

An active intermediate formed in the reaction of bleomycin-Fe(II) complex with oxygen

30 October 2022

108

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Ferric bleomycin catalyzed reduction of 10-hydroperoxy-8,12-octadecadienoic acid: evidence for homolytic O-O bond scission

30 October 2022

113

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The production of hydroxyl radical by bleomycin and iron (ii)

30 October 2022

116

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Iron(II)-bleomycin. Biochemical and spectral properties in the presence of radical scavengers

30 October 2022

119

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The crypto-OH· radical in the damage of dna by bleomycin-Fe2+?

30 October 2022

120

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA breaks generated by the bleomycin-iron III complex in the presence of KHSO5, a single oxygen donor

30 October 2022

124

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Evidence for high-valent iron-oxo species active in the DNA breaks mediated by iron-bleomycin

30 October 2022

125

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Production of free radicals from phenol and tocopherol by bleomycin-iron(II) complex

30 October 2022

126

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin A2: a ferrous oxidase

30 October 2022

129

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Intermediates in the ferrous oxidase cycle of bleomycin

30 October 2022

130

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Effect of deoxyribonucleic acid on the production of reduced oxygen by bleomycin and iron

30 October 2022

131

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Catalytic release of deoxyribonucleic acid bases by oxidation and reduction of an iron .cntdot. bleomycin complex

30 October 2022

132

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA strand scission by enzymically generated oxygen radicals

30 October 2022

134

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Role of metals in oxygen radical reactions

30 October 2022

135

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Role of superoxide in deoxyribonucleic acid strand scission

30 October 2022

139

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Dimethyl sulfoxide prevents DNA nicking mediated by ionizing radiation or iron/hydrogen peroxide-generated hydroxyl radical

30 October 2022

140

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA-ferrous iron catalyzed hydroxyl free radical formation from hydrogen peroxide

30 October 2022

141

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The production of hydroxyl radical from copper(I) complex systems of bleomycin and tallysomycin: Comparison with copper(II) and iron(II) systems

30 October 2022

142

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Reduction of copper(II)-bleomycin: a model for in vivo drug activity

30 October 2022

143

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The nature of thiol-compounds which trap cuprous ion reductively liberated from bleomycin-Cu(II) in cells

30 October 2022

144

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Mononuclear and binuclear Co(III)-dioxygen adducts of bleomycin. Circular dichroism and electron paramagnetic resonance studies

30 October 2022

146

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Studies on Bleomycin-DNA and Bleomycin-Iron Interactions

30 October 2022

150

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin-DNA interactions: fluorescence and proton magnetic resonance studies

30 October 2022

151

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interactions of bleomycin analogues with deoxyribonucleic acid and metal ions studied by fluorescence quenching

30 October 2022

152

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin-A2 complexes with poly(dA-dT): A proton nuclear magnetic resonance study of the nonexchangeable hydrogens

30 October 2022

153

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin interactions with DNA. Studies on the role of the C-terminal cationic group of bleomycin A2 in association with and degradation of DNA

30 October 2022

154

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Binding of bleomycin to DNA: intercalation of the bithiazole rings

30 October 2022

155

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Copper(II).bleomycin, iron(III).bleomycin, and copper(II).phleomycin: comparative study of deoxyribonucleic acid binding

30 October 2022

156

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interactions of a fragment of bleomycin with deoxyribodinucleotides: nuclear magnetic resonance studies

30 October 2022

157

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interaction of bleomycin A2 with poly(deoxyadenylylthymidylic acid). A proton nuclear magnetic resonance study of the influence of temperature, pH, and ionic strength

30 October 2022

158

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interaction of bleomycin A2 with deoxyribonucleic acid: DNA unwinding and inhibition of bleomycin-induced DNA breakage by cationic thiazole amides related to bleomycin A2

30 October 2022

159

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Is the bithiazole moiety of bleomycin a classical intercalator?

30 October 2022

160

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Interactions of molecules with nucleic acids. XII. Theoretical model for the interaction of a fragment of bleomycin with DNA

30 October 2022

161

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Models of bleomycin interactions with poly(dA-dT). Fluorescence and proton nuclear magnetic resonance studies of cationic thiazole amides related to bleomycin A2

30 October 2022

162

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Synthesis and DNA binding of [3-[2'-(2-acetamidoethyl)-2,4'-bithiazole-4-carboxamido]propyl]dimethylsulfonium chloride, a fragment of bleomycin A2

30 October 2022

163

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin analogs. Phenylthiazole models of the bithiazole moiety of bleomycin A2

30 October 2022

164

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA Modification and Cancer

30 October 2022

165

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA-drug binding and control of genetic information

30 October 2022

166

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Specificity of deoxyribonucleic acid cleavage by bleomycin, phleomycin, and tallysomycin

30 October 2022

169

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Sequence-specific recognition and cleavage of DNA by metallobleomycin: minor groove binding and possible interaction mode

30 October 2022

170

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The conformation and orientation of copper(II)-bleomycin intercalated with DNA

30 October 2022

171

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The orientation of the ligands in iron(III)-bleomycin intercalated with DNA

30 October 2022

172

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Iron-bleomycin-deoxyribonucleic acid system. Evidence of deoxyribonucleic acid interaction with the .alpha.-amino group of the .beta.-aminoalanine moiety

30 October 2022

175

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Copper(II) facilitates bleomycin-mediated unwinding of plasmid DNA.

30 October 2022

176

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Oxidation-reduction reactions of iron bleomycin in the absence and presence of DNA

30 October 2022

178

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Fragmentation of deoxyribonucleic acid by bleomycin

30 October 2022

180

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin-specific fragmentation of double-stranded DNA.

30 October 2022

181

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Specificity of DNA base release by bleomycin

30 October 2022

183

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Strand-scission of DNA by neocarzinostatin, auromomycin, and bleomycin: studies on base release and nucleotide sequence specificity

30 October 2022

184

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Specificity of deoxyribonucleic acid cleavage by bleomycin, phleomycin, and tallysomycin

30 October 2022

186

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin and talisomycin sequence-specific strand scission of DNA: a mechanism of double-strand cleavage

30 October 2022

187

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Role of deoxyribonucleic acid topology in altering the site/sequence specificity of cleavage of deoxyribonucleic acid by bleomycin and talisomycin

30 October 2022

188

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Comparison of the sequence specificity of bleomycin cleavage in two slightly different DNA sequences

30 October 2022

190

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA methylation diminishes bleomycin-mediated strand scission

30 October 2022

191

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Nucleotide sequence cleavage of guanine-modified DNA with aflatoxin B1, dimethyl sulfate, and mitomycin C by bleomycin and deoxyribonuclease I

30 October 2022

192

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Site specificity of bleomycin cleavage in purified and intracellular simian virus 40 DNA.

30 October 2022

194

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA double-strand breaks and alkali-labile bonds produced by bleomycin

30 October 2022

196

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

30 October 2022

197

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin causes release of nucleosomes from chromatin and chromosomes

30 October 2022

198

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Immediate and repair induced DNA double strand breaks in mammalian cells

30 October 2022

200

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Effect of apurinic/apyrimidinic endonucleases and polyamines on DNA treated with bleomycin and neocarzinostatin: specific formation and cleavage of closely opposed lesions in complementary strands

30 October 2022

202

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines

30 October 2022

203

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Cytotoxic base propenals and the action of bleomycin

30 October 2022

205

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Bleomycin-induced aggregation of presolubilized and nuclear chromatin from L1210 cells

30 October 2022

206

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Preferential effect of bleomycin on newly replicated chromatin in nuclei from L1210 cells

30 October 2022

207

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

The effect of bleomycin on prolyl hydroxylase and DNA chain breakage: Structure-activity relationship

30 October 2022

208

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Iron·bleomycin·DNA·system evidence of a long-lived bleomycin·iron·oxygen intermediate

30 October 2022

209

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage

30 October 2022

211

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Studies on the interaction of bleomycin A2 with rat lung microsomes. III. Effect of exogenous iron on bleomycin-mediated DNA chain breakage

30 October 2022

213

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Redox cycling of bleomycin-Fe(III) and DNA degradation by isolated NADH-cytochrome b5 reductase: involvement of cytochrome b5

30 October 2022

215

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Redox cycling of bleomycin-Fe(III) by an NADH-dependent enzyme, and DNA damage in isolated rat liver nuclei.

30 October 2022

216

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Redox cycling of Fe(III)-bleomycin by NADPH-cytochrome P-450 reductase

30 October 2022

217

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Self-inactivation of Fe(II)-bleomycin

30 October 2022

221

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Vanadyl binding to bleomycin

30 October 2022

224

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

First evidences of the formation of a vanadyl(IV) complex of bleomycin

30 October 2022

225

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Effective DNA cleavage by bleomycin-vanadium(IV) complex plus hydrogen peroxide

30 October 2022

226

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Differences in the cleavage of DNA by bleomycin under light (300–350 nm) and dark conditions

30 October 2022

227

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Single-strand scission and repair of DNA in mammalian cells by bleomycin

30 October 2022

231

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https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Rapid and slow DNA rejoining in nondividing human diploid fibroblasts treated with bleomycin and ionizing radiation

30 October 2022

232

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Lack of metabolism as the biochemical basis of bleomycin-induced pulmonary toxicity

30 October 2022

235

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

DNA damage and growth inhibition in cultured human cells by bleomycin congeners

30 October 2022

239

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Effects of iron, copper, cobalt, and their chelators on the cytotoxicity of bleomycin

30 October 2022

241

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

Letter: A metabolite of bleomycin A5 in rabbit urine

30 October 2022

243

1 reference

https://api.crossref.org/works/10.1016/0009-2797(90)90001-4

30 October 2022

Identifiers

1 reference

14 August 2017

1 reference