Drug-induced mitochondrial toxicity (Q36544880)

14 August 2017

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title

Drug-induced mitochondrial toxicity (English)

1 reference

14 August 2017

Katie Chan

1

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14 August 2017

Don Truong

series ordinal

2

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14 August 2017

Nandita Shangari

series ordinal

3

1 reference

14 August 2017

Peter J O'Brien

series ordinal

4

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14 August 2017

language of work or name

English

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publication date

1 December 2005

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Expert Opinion on Drug Metabolism & Toxicology

14 August 2017

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14 August 2017

1

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14 August 2017

4

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14 August 2017

655-669

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Life's smile, death's grin: vital functions of apoptosis-executing proteins

14 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Metformin-associated lactic acidosis: a rare or very rare clinical entity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondria-based model for fetal origin of adult disease and insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Rotenone, deguelin, their metabolites, and the rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Endogenous and endobiotic induced reactive oxygen species formation by isolated hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Coenzyme Q cytoprotective mechanisms for mitochondrial complex I cytopathies involves NAD(P)H: quinone oxidoreductase 1(NQO1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Modulating hypoxia-induced hepatocyte injury by affecting intracellular redox state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Superoxide anion generation by the cytochrome bc1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced complex I inhibition is reversed by disulfide reductant, dithiothreitol in mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of mitochondrial complex I by haloperidol: the role of thiol oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of complex I by neuroleptics in normal human brain cortex parallels the extrapyramidal toxicity of neuroleptics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Studies on the metabolism of haloperidol (HP): the role of CYP3A in the production of the neurotoxic pyridinium metabolite HPP+ found in rat brain following ip administration of HP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Absence of stereospecific effects of bupivacaine isomers on heart mitochondrial bioenergetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of cytochrome oxidase activity by local anaesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of cytochrome oxidase by dibucaine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondrial injury and caspase activation by the local anesthetic lidocaine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Effects of troglitazone on HepG2 viability and mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Peroxidases: a role in the metabolism and side effects of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Troglitazone-induced intracellular oxidative stress in rat hepatoma cells: a flow cytometric assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mechanisms of troglitazone hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Effects of ring substituents on the activity of phenols as inhibitors and uncouplers of mitochondrial respiration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Effects of entacapone and tolcapone on mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Comparative QSAR evidence for a free-radical mechanism of phenol-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Quantitative structure toxicity relationships for phenols in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Parametrization of electrophilicity for the prediction of the toxicity of aromatic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Toxicity of amiodarone and amiodarone analogues on isolated rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Metabolic effects of propofol in the isolated perfused rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Propofol suppresses macrophage functions and modulates mitochondrial membrane potential and cellular adenosine triphosphate synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Quantitative analysis of uncoupling activity of substituted phenols with a physicochemical substituent and molecular parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Uncoupling of intestinal mitochondrial oxidative phosphorylation and inhibition of cyclooxygenase are required for the development of NSAID-enteropathy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Application of quantitative structure-toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Comparison of the effects of bupivacaine and ropivacaine on heart cell mitochondrial bioenergetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Bupivacaine myotoxicity is mediated by mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Effect of local anesthetic ropivacaine on isolated rat liver mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Effect of change in cellular GSH levels on mitochondrial damage and cell viability loss due to mitomycin c in small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Differential effect of nitrogen species on changes in mitochondrial membrane permeability due to mitomycin c in lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Dexrazoxane (ICRF-187) Protects Cardiac Myocytes Against Doxorubicin by Preventing Damage to Mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of doxorubicin chronic toxicity in catalase-overexpressing transgenic mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Carvedilol protects against doxorubicin-induced mitochondrial cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mechanism of clofibrate hepatotoxicity: mitochondrial damage and oxidative stress in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Inhibition of mitochondrial respiration and oxygen-dependent hepatotoxicity by six structurally dissimilar peroxisomal proliferating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mechanisms of benzarone and benzbromarone-induced hepatic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Concentration dependent mitochondrial effect of amiodarone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Megamitochondria formation - physiology and pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Hydrogen peroxide overproduction in megamitochondria of troglitazone-treated human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Azidothymidine causes functional and structural destruction of mitochondria, glutathione deficiency and HIV-1 promoter sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondrial oxidative stress in human hepatoma cells exposed to stavudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

[13C]Methionine breath test: a novel method to detect antiretroviral drug-related mitochondrial toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.1.4.655

21 January 2018

Identifiers

DOI

10.1517/17425255.1.4.655

1 reference

14 August 2017

1 reference