Multidrug-resistance efflux pumps - not just for resistance (Q36538111)

14 August 2017

1 reference

title

Multidrug-resistance efflux pumps - not just for resistance (English)

1 reference

14 August 2017

multiple drug resistance

1 reference

Laura J V Piddock

1

1 reference

PubMed ID

16845433

14 August 2017

language of work or name

English

0 references

publication date

1 August 2006

1 reference

Nature Reviews Microbiology

14 August 2017

1 reference

14 August 2017

4

1 reference

14 August 2017

8

1 reference

14 August 2017

629-636

1 reference

https://scigraph.springernature.com/pub.10.1038/nrmicro1464

14 August 2017

0 references

cites work

Structure and function of efflux pumps that confer resistance to drugs

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multidrug efflux pumps and resistance: regulation and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Efflux-mediated multiresistance in Gram-negative bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Efflux-mediated antimicrobial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Efflux pumps and nosocomial antibiotic resistance: a primer for hospital epidemiologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The TetR family of transcriptional repressors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Structure and function of TolC: the bacterial exit duct for proteins and drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Aminoglycosides are captured from both periplasm and cytoplasm by the AcrD multidrug efflux transporter of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Three's company: component structures bring a closer view of tripartite drug efflux pumps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: resistance to tetracycline, chloramphenicol, and norfloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Linezolid in vitro: mechanism and antibacterial spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

PDF inhibitors: an emerging class of antibacterial drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The AcrAB-TolC pump is involved in macrolide resistance but not in telithromycin efflux in Enterobacter aerogenes and Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Efflux-mediated resistance to tigecycline (GAR-936) in Pseudomonas aeruginosa PAO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

AcrAB multidrug efflux pump is associated with reduced levels of susceptibility to tigecycline (GAR-936) in Proteus mirabilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multidrug efflux in Pseudomonas aeruginosa: components, mechanisms and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Role of efflux pumps and mutations in genes for topoisomerases II and IV in fluoroquinolone-resistant Pseudomonas aeruginosa strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Genetic and phenotypic variations of a resistant Pseudomonas aeruginosa epidemic clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multiple antibiotic resistance and efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Solvent tolerance in bacteria: role of efflux pumps and cross-resistance with antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Role of the acrAB locus in organic solvent tolerance mediated by expression of marA, soxS, or robA in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

AcrD of Escherichia coli is an aminoglycoside efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multidrug resistance mechanisms: drug efflux across two membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

High-level fluoroquinolone-resistant clinical isolates of Escherichia coli overproduce multidrug efflux protein AcrA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Absence of mutations in marRAB or soxRS in acrB-overexpressing fluoroquinolone-resistant clinical and veterinary isolates of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Expression of acrB, acrF, acrD, marA, and soxS in Salmonella enterica serovar Typhimurium: role in multiple antibiotic resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

AcrAB-TolC directs efflux-mediated multidrug resistance in Salmonella enterica serovar typhimurium DT104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Evidence for active efflux as the primary mechanism of resistance to ciprofloxacin in Salmonella enterica serovar typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Evidence for an efflux pump mediating multiple antibiotic resistance in Salmonella enterica serovar Typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Ciprofloxacin resistance in clinical isolates of Salmonella typhimurium obtained from two patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Quinolone-resistant Salmonella typhi in Viet Nam: molecular basis of resistance and clinical response to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

An outbreak of multidrug-resistant, quinolone-resistant Salmonella enterica serotype typhimurium DT104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Identification and molecular characterisation of CmeB, a Campylobacter jejuni multidrug efflux pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

CmeABC functions as a multidrug efflux system in Campylobacter jejuni

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Expression of the efflux pump genes cmeB, cmeF and the porin gene porA in multiple-antibiotic-resistant Campylobacter jejuni.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Evidence for multiple-antibiotic resistance in Campylobacter jejuni not mediated by CmeB or CmeF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Critical role of multidrug efflux pump CmeABC in bile resistance and in vivo colonization of Campylobacter jejuni

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The multidrug efflux transporter of Bacillus subtilis is a structural and functional homolog of the Staphylococcus NorA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Quinolone resistance mediated by norA: physiologic characterization and relationship to flqB, a quinolone resistance locus on the Staphylococcus aureus chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Comparison of the nucleotide sequence and expression of norA genes and microbial susceptibility in 21 strains of Staphylococcus aureus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Relationship between mutations in the coding and promoter regions of the norA genes in 42 unrelated clinical isolates of Staphylococcus aureus and the MICs of norfloxacin for these strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Relationship between mutations in the DNA gyrase and topoisomerase IV genes and nadifloxacin resistance in clinically isolated quinolone-resistant Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Expression of efflux pump gene pmrA in fluoroquinolone-resistant and -susceptible clinical isolates of Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Involvement of the putative ATP-dependent efflux proteins PatA and PatB in fluoroquinolone resistance of a multidrug-resistant mutant of Streptococcus pneumoniae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Macrolide efflux in Streptococcus pneumoniae is mediated by a dual efflux pump (mel and mef) and is erythromycin inducible

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Salmonella enteritidis has a homologue of tolC that is required for virulence in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

TolC but not AcrB is essential for multidrug-resistant Salmonella enterica serotype Typhimurium colonization of chicks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The AcrAB-TolC efflux system of Salmonella enterica serovar Typhimurium plays a role in pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multidrug efflux systems play an important role in the invasiveness of Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The phytoalexin-inducible multidrug efflux pump AcrAB contributes to virulence in the fire blight pathogen, Erwinia amylovora.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

NorM, an Erwinia amylovora multidrug efflux pump involved in in vitro competition with other epiphytic bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Synthesis, maturation and export of the E. coli hemolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Protein secretion by Gram-negative bacterial ABC exporters--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

The hemolysin of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Vibrio cholerae tolC is required for bile resistance and colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Vibrio cholerae strains with mutations in an atypical type I secretion system accumulate RTX toxin intracellularly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in an experimental model of Pseudomonas aeruginosa acute pneumonia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Protein secretion and the pathogenesis of bacterial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Communication in bacteria: an ecological and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Quorum sensing and multidrug transporters in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Bile-salt-mediated induction of antimicrobial and bile resistance in Salmonella typhimurium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Induction of the mtrCDE-encoded efflux pump system of Neisseria gonorrhoeae requires MtrA, an AraC-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Mammalian steroid hormones are substrates for the major RND- and MFS-type tripartite multidrug efflux pumps of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Bacteria lacking a multidrug pump: a sensitive tool for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

In vivo emergence of multidrug-resistant mutants of Pseudomonas aeruginosa overexpressing the active efflux system MexA-MexB-OprM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Multiple mutations conferring ciprofloxacin resistance in Staphylococcus aureus demonstrate long-term stability in an antibiotic-free environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Identification of an efflux pump gene, pmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Molecular mechanisms of Salmonella pathogenesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1464

31 March 2020

Identifiers

DOI

10.1038/NRMICRO1464

1 reference

PubMed ID

16845433

Dimensions Publication ID

14 August 2017

0 references

1 reference

PubMed ID

16845433