Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa (Q36525867)

14 August 2017

Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa (English)

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14 August 2017

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Katherine J Wert

1

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14 August 2017

Richard J Davis

2

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14 August 2017

Javier Sancho-Pelluz

3

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14 August 2017

Patsy M Nishina

4

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14 August 2017

Stephen H Tsang

5

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14 August 2017

29 October 2012

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14 August 2017

Human Molecular Genetics

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14 August 2017

22

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14 August 2017

3

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14 August 2017

558-567

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Lentivirus-mediated expression of cDNA and shRNA slows degeneration in retinitis pigmentosa

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

New mouse models for recessive retinitis pigmentosa caused by mutations in the Pde6a gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Functional rescue of degenerating photoreceptors in mice homozygous for a hypomorphic cGMP phosphodiesterase 6 b allele (Pde6bH620Q).

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Perspective on genes and mutations causing retinitis pigmentosa

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Rescue from photoreceptor degeneration in the rd mouse by human immunodeficiency virus vector-mediated gene transfer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Encapsidated adenovirus mini-chromosome-mediated delivery of genes to the retina: application to the rescue of photoreceptor degeneration

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Retinitis pigmentosa and allied diseases. Implications of genetic heterogeneity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Retinal degeneration is rescued in transgenic rd mice by expression of the cGMP phosphodiesterase beta subunit

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Complete cDNA sequences of mouse rod photoreceptor cGMP phosphodiesterase α- and β-subunits, and identification of β′-, a putative β-subunit isozyme produced by alternative splicing of the β-subunit gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

A computational model of the amplitude and implicit time of the b-wave of the human ERG

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Retinal transplants restore visually evoked responses in rats with photoreceptor degeneration.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Rescue of photoreceptor function by AAV-mediated gene transfer in a mouse model of inherited retinal degeneration

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Rod phototransduction in retinitis pigmentosa: estimation and interpretation of parameters derived from the rod a-wave.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3542865

Subunit stoichiometry of retinal rod cGMP phosphodiesterase

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23108158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Injury-induced upregulation of bFGF and CNTF mRNAS in the rat retina

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23108158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23108158

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDS466

1 reference

14 August 2017

1 reference

14 August 2017

1 reference