Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes. (Q36521105)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16804197%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

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title

Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes (English)

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25 December 2019

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2

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25 December 2019

1

Aleksey V Matveyenko

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25 December 2019

publication date

1 January 2006

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25 December 2019

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25 December 2019

volume

47

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25 December 2019

page(s)

225-233

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25 December 2019

issue

3

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Transgenic overexpression of human islet amyloid polypeptide inhibits insulin secretion and glucose elimination after gastric glucose gavage in mice.

25 December 2019

cites work

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Islet amyloid polypeptide (IAPP):cDNA cloning and identification of an amyloidogenic region associated with the species-specific occurrence of age-related diabetes mellitus

21 January 2018

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Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

21 January 2018

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

21 January 2018

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Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid

21 January 2018

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Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans.

21 January 2018

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Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men.

21 January 2018

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

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Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

21 January 2018

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Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

21 January 2018

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Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell death

21 January 2018

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Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats

21 January 2018

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Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

21 January 2018

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Longitudinal studies on the development of diabetes in individual Macaca nigra

21 January 2018

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Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid

21 January 2018

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Genetic background determines the extent of islet amyloid formation in human islet amyloid polypeptide transgenic mice.

21 January 2018

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The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

21 January 2018

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Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

21 January 2018

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Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice

21 January 2018

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Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections

21 January 2018

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Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

21 January 2018

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The role of amylin in the insulin resistance of non-insulin-dependent diabetes mellitus

21 January 2018

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Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

21 January 2018

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Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

21 January 2018

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Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

21 January 2018

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Islet amyloid polypeptide in human insulinomas. Evidence for intracellular amyloidogenesis

21 January 2018

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Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus

21 January 2018

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Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

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Contribution of abnormal insulin secretion and insulin resistance to the pathogenesis of type 2 diabetes in myotonic dystrophy

21 January 2018

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Leptin receptor missense mutation in the fatty Zucker rat.

21 January 2018

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beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony

21 January 2018

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Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis.

21 January 2018

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Emerging epidemic of type 2 diabetes in youth

21 January 2018

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Isoproterenol-stimulated C-peptide and insulin secretion in diabetic and nonobese normal subjects: decreased hepatic extraction of endogenous insulin in diabetes.

21 January 2018

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Psammomys obesus of the Jerusalem colony: a model for nutritionally induced, non-insulin-dependent diabetes

21 January 2018

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Nutritionally induced insulin resistance and receptor defect leading to beta-cell failure in animal models

21 January 2018

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Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

21 January 2018

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High prevalence of hepatitis C virus infection in diabetic patients

21 January 2018

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Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

21 January 2018

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

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21 January 2018

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Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.

21 January 2018

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Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

21 January 2018

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Comparison of body size measurements as predictors of NIDDM in Pima Indians.

21 January 2018

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Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study

21 January 2018

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Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1093/ILAR.47.3.225

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16804197%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference