CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. (Q36515088)

14 August 2017

CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5. (English)

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14 August 2017

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Yong-Jing Gao

11

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Temugin Berta

object named as

Temugin Berta

9

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Ru-Rong Ji

object named as

Ru-Rong Ji

10

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author name string

Bao-Chun Jiang

1

1 reference

14 August 2017

De-Li Cao

2

1 reference

14 August 2017

Xin Zhang

3

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14 August 2017

Zhi-Jun Zhang

4

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14 August 2017

Li-Na He

5

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14 August 2017

Chun-Hua Li

6

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14 August 2017

Wen-Wen Zhang

7

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14 August 2017

Xiao-Bo Wu

8

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14 August 2017

language of work or name

English

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publication date

11 January 2016

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Journal of Clinical Investigation

14 August 2017

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14 August 2017

126

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14 August 2017

2

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14 August 2017

745-761

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TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling

14 August 2017

1 reference

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Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2.

30 September 2017

1 reference

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Extracellular microRNAs activate nociceptor neurons to elicit pain via TLR7 and TRPA1

30 September 2017

1 reference

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Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion

30 September 2017

1 reference

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Chemokine contribution to neuropathic pain: respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons

30 September 2017

1 reference

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Glia and pain: is chronic pain a gliopathy?

30 September 2017

1 reference

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Tissue plasminogen activator contributes to morphine tolerance and induces mechanical allodynia via astrocytic IL-1β and ERK signaling in the spinal cord of mice

30 September 2017

1 reference

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Spinal astrocytic activation contributes to mechanical allodynia in a rat chemotherapy-induced neuropathic pain model

30 September 2017

1 reference

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miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation.

30 September 2017

1 reference

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Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury

30 September 2017

1 reference

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Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy

30 September 2017

1 reference

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Chemokine mediated neuron-glia communication and aberrant signalling in neuropathic pain states

30 September 2017

1 reference

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Chemokines and cytokines in neuroinflammation leading to neuropathic pain

30 September 2017

1 reference

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Induction of the P2X7 receptor in spinal microglia in a neuropathic pain model

30 September 2017

1 reference

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The response of spinal microglia to chemotherapy-evoked painful peripheral neuropathies is distinct from that evoked by traumatic nerve injuries

30 September 2017

1 reference

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The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system

30 September 2017

1 reference

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Possible role of glial cells in the onset and progression of Lyme neuroborreliosis

30 September 2017

1 reference

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JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain

30 September 2017

1 reference

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MicroRNAs: target recognition and regulatory functions

30 September 2017

1 reference

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30 September 2017

1 reference

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Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal apoptosis

30 September 2017

1 reference

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MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X7 receptor by activation of instability sites at the 3'-untranslated region of the gene that decrease steady-state levels of the transcript

30 September 2017

1 reference

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Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord

30 September 2017

1 reference

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Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

30 September 2017

1 reference

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Chemokines and the pathophysiology of neuropathic pain

30 September 2017

1 reference

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Chemokines and chemokine receptors in neurological disease: raise, retain, or reduce?

30 September 2017

1 reference

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Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21

30 September 2017

1 reference

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CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.

30 September 2017

1 reference

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The many roles of chemokines and chemokine receptors in inflammation

30 September 2017

1 reference

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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

30 September 2017

1 reference

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The nervous system as ectopic germinal center: CXCL13 and IgG in lyme neuroborreliosis

30 September 2017

1 reference

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Central sensitization and LTP: do pain and memory share similar mechanisms?

30 September 2017

1 reference

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P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

30 September 2017

1 reference

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Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2

30 September 2017

1 reference

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Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells

30 September 2017

1 reference

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A chemokine-driven positive feedback loop organizes lymphoid follicles

30 September 2017

1 reference

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Chemokines in the CNS: plurifunctional mediators in diverse states

30 September 2017

1 reference

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Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

30 September 2017

1 reference

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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

30 September 2017

1 reference

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An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

miR-7a alleviates the maintenance of neuropathic pain through regulation of neuronal excitability.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain

28 June 2018

1 reference

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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1

28 June 2018

1 reference

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Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Epigenetic transcriptional activation of monocyte chemotactic protein 3 contributes to long-lasting neuropathic pain.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Spinal P2X(7) receptor mediates microglia activation-induced neuropathic pain in the sciatic nerve injury rat model.

21 September 2018

1 reference

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Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS.

21 September 2018

1 reference

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CXCL13 and CXCL12 in central nervous system lymphoma patients.

21 September 2018

1 reference

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The P2X7 receptor drives microglial activation and proliferation: a trophic role for P2X7R pore

21 September 2018

1 reference

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Interleukin-18-mediated microglia/astrocyte interaction in the spinal cord enhances neuropathic pain processing after nerve injury.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain

21 September 2018

1 reference

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Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment.

21 September 2018

1 reference

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Fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) distribution in spinal cord and dorsal root ganglia under basal and neuropathic pain conditions

21 September 2018

1 reference

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Complete Freunds adjuvant-induced peripheral inflammation evokes glial activation and proinflammatory cytokine expression in the CNS.

21 September 2018

1 reference

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Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

ERK integrates PKA and PKC signaling in superficial dorsal horn neurons. I. Modulation of A-type K+ currents.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.

21 September 2018

1 reference

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Evidence for activation of astrocytes via reactive microglial cells following hypoglossal nerve transection.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Reduced inflammatory and neuropathic pain and decreased spinal microglial response in fractalkine receptor (CX3CR1) knockout mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Expression of CCR2 in Both Resident and Bone Marrow-Derived Microglia Plays a Critical Role in Neuropathic Pain

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Spatial and temporal relationship between monocyte chemoattractant protein-1 expression and spinal glial activation following peripheral nerve injury

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4731172

Pronociceptive actions of dynorphin maintain chronic neuropathic pain

4 December 2018

1 reference

12 December 2020

Spinal astrocytic activation contributes to mechanical allodynia in a mouse model of type 2 diabetes

1 reference

12 December 2020

miR-186, miR-3651 and miR-494: Potential biomarkers for oral squamous cell carcinoma extracted from whole blood

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12 December 2020

Induction of CX3CL1 expression in astrocytes and CX3CR1 in microglia in the spinal cord of a rat model of neuropathic pain

1 reference

12 December 2020

CXC chemokine ligand 13 plays a role in experimental autoimmune encephalomyelitis

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12 December 2020

Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections

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CSF B--lymphocyte chemoattractant (CXCL13) in the early diagnosis of acute Lyme neuroborreliosis

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12 December 2020

Identifiers

DOI

10.1172/JCI81950

1 reference

14 August 2017

1 reference

14 August 2017

1 reference