Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice (Q36509312)

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scientific article published on July 2009

Language	Label	Description	Also known as
English	Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice	scientific article published on July 2009

Statements

scholarly article

1 reference

Europe PubMed Central

14 August 2017

Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice (English)

1 reference

Europe PubMed Central

14 August 2017

author name string

Sean O Ryan

1

1 reference

Europe PubMed Central

14 August 2017

Anda M Vlad

2

1 reference

Europe PubMed Central

14 August 2017

Kazi Islam

3

1 reference

Europe PubMed Central

14 August 2017

Jean Gariépy

4

1 reference

Europe PubMed Central

14 August 2017

Olivera J Finn

5

1 reference

Europe PubMed Central

14 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 July 2009

1 reference

Europe PubMed Central

14 August 2017

Biological Chemistry

1 reference

Europe PubMed Central

14 August 2017

390

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Europe PubMed Central

14 August 2017

7

1 reference

Europe PubMed Central

14 August 2017

611-618

1 reference

Europe PubMed Central

14 August 2017

A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Multiple roles for CD4+ T cells in anti-tumor immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Tumor antigen-based immunotherapy and immunoprevention of cancer

1 reference

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Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

1 reference

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The cooperation between two CD4 T cells induces tumor protective immunity in MUC.1 transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Glycoprotein tumor antigens for immunotherapy of breast cancer.

1 reference

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30 September 2017

Designer glycopeptides for cytotoxic T cell-based elimination of carcinomas

1 reference

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30 September 2017

Nuclear magnetic resonance-based dissection of a glycosyltransferase specificity for the mucin MUC1 tandem repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

MHC-restricted, glycopeptide-specific T cells show specificity for both carbohydrate and peptide residues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

30 September 2017

Immunoreactive T and Tn epitopes in cancer diagnosis, prognosis, and immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

28 June 2018

Two better cell lines for making hybridomas expressing specific T cell receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

28 June 2018

The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

21 September 2018

On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes

1 reference

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21 September 2018

HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

21 September 2018

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4729297

4 December 2018

Lack of effective MUC1 tumor antigen-specific immunity in MUC1-transgenic mice results from a Th/T regulatory cell imbalance that can be corrected by adoptive transfer of wild-type Th cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducing and expanding regulatory T cell populations by foreign antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immature human dendritic cells express asialoglycoprotein receptor isoforms for efficient receptor-mediated endocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of unresponsiveness to circulating tumor antigen MUC1 is a block in intracellular sorting and processing by dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ lymphocytes provide MUC1-specific tumor immunity in vivo that is undetectable in vitro and is absent in MUC1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

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based on heuristic

inferred from PubMed ID database lookup

Novel synthetic LPS receptor agonists boost systemic and mucosal antibody responses in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19426130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1515/BC.2009.070

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

1 reference

Europe PubMed Central

14 August 2017

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