The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. (Q36509173)

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28 December 2019

title

The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis (English)

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28 December 2019

6

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28 December 2019

Adrian Goldman

7

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28 December 2019

author name string

Yan Xiong

1

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28 December 2019

Anne-Sisko Patana

2

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28 December 2019

Michael J Miley

3

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28 December 2019

Agnieszka K Zielinska

4

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28 December 2019

Stacie M Bratton

5

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28 December 2019

Moshe Finel

8

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28 December 2019

Matt R Redinbo

9

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28 December 2019

Anna Radominska-Pandya

10

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28 December 2019

publication date

29 November 2007

1 reference

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Drug Metabolism and Disposition

28 December 2019

published in

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28 December 2019

volume

36

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28 December 2019

issue

3

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28 December 2019

page(s)

517-522

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Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7

28 December 2019

cites work

1 reference

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Structures and mechanisms of glycosyltransferases

30 September 2017

1 reference

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The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation

30 September 2017

1 reference

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The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Structural and functional studies of UDP-glucuronosyltransferases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Photoaffinity labeling of the aglycon binding site of the recombinant human liver UDP-glucuronosyltransferase UGT1A6 with 7-azido-4-methylcoumarin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Cloning and expression of solanidine UDP-glucose glucosyltransferase from potato.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

The novel bilirubin/phenol UDP-glucuronosyltransferase UGT1 gene locus: implications for multiple nonhemolytic familial hyperbilirubinemia phenotypes

30 September 2017

1 reference

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Expression of chimeric cDNAs in cell culture defines a region of UDP glucuronosyltransferase involved in substrate selection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Opioids bind to the amino acids 84 to 118 of UDP-glucuronosyltransferase UGT2B7.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2275115

The human UDP-glucuronosyltransferase: identification of key residues within the nucleotide-sugar binding site

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18048489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Importance of histidine residues for the function of the human liver UDP-glucuronosyltransferase UGT1A6: evidence for the catalytic role of histidine 370

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18048489

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/DMD.107.016469

1 reference

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release_h3rga3nyl5fqvp75bou4mzocui

28 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/h3rga3nyl5fqvp75bou4mzocui

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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28 December 2019

PubMed publication ID

18048489

1 reference