Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes. (Q36486085)

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English	Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes.	scientific article

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18 February 2020

Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes (English)

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18 February 2020

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toll-like receptor

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Carole R Mendelson

3

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18 February 2020

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Alina P Montalbano

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18 February 2020

Samuel Hawgood

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26 November 2012

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18 February 2020

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18 February 2020

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18 February 2020

483-498

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18 February 2020

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18 February 2020

Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A-stimulated macrophage chemotaxis

1 reference

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30 September 2017

An Insight into the Diverse Roles of Surfactant Proteins, SP-A and SP-D in Innate and Adaptive Immunity

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30 September 2017

National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications

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30 September 2017

Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation

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30 September 2017

Toll-like receptor 2-mediated sequential activation of MyD88 and MAPKs contributes to lipopolysaccharide-induced sp-a gene expression in human alveolar epithelial cells

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30 September 2017

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

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30 September 2017

Mouse gestation length is genetically determined

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30 September 2017

Review: Structural determinants of pattern recognition by lung collectins.

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30 September 2017

TLR2 mediates gap junctional intercellular communication through connexin-43 in intestinal epithelial barrier injury

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30 September 2017

Integration of endocrine and mechanical signals in the regulation of myometrial functions during pregnancy and labour

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30 September 2017

Minireview: fetal-maternal hormonal signaling in pregnancy and labor

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30 September 2017

Inflammation and pregnancy.

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30 September 2017

Monocyte chemoattractant protein-1 (CCL-2) integrates mechanical and endocrine signals that mediate term and preterm labor

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30 September 2017

Myometrial mechanoadaptation during pregnancy: implications for smooth muscle plasticity and remodelling

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30 September 2017

TLR2 regulates gap junction intercellular communication in airway cells

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30 September 2017

Epidemiology and causes of preterm birth

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30 September 2017

Pulmonary collectins in innate immunity of the lung

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30 September 2017

The role of inflammation and infection in preterm birth

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30 September 2017

Preterm labor is induced by intraamniotic infusions of interleukin-1beta and tumor necrosis factor-alpha but not by interleukin-6 or interleukin-8 in a nonhuman primate model

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30 September 2017

Human pulmonary surfactant protein D binds the extracellular domains of Toll-like receptors 2 and 4 through the carbohydrate recognition domain by a mechanism different from its binding to phosphatidylinositol and lipopolysaccharide

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30 September 2017

Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response. Importance of supratrimeric oligomerization

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30 September 2017

In defense of the lung: surfactant protein A and surfactant protein D.

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30 September 2017

The molecular pathophysiology of bacterially induced preterm labor: insights from the murine model

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30 September 2017

Immunoregulatory functions of surfactant proteins

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30 September 2017

The lung collectins, SP-A and SP-D, modulate pulmonary innate immunity

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Animal models of preterm birth.

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30 September 2017

Endogenous ligands of Toll-like receptors

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30 September 2017

Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition

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30 September 2017

By Binding SIRPα or Calreticulin/CD91, Lung Collectins Act as Dual Function Surveillance Molecules to Suppress or Enhance Inflammation

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30 September 2017

Cytokines, prostaglandins and parturition--a review

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30 September 2017

Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A.

1 reference

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30 September 2017

IL-13 receptors and signaling pathways: An evolving web

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30 September 2017

Hydrophobic surfactant proteins in lung function and disease

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30 September 2017

Toll-like receptors and innate immunity

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30 September 2017

Innate immune recognition

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30 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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30 September 2017

CCL27-CCR10 interactions regulate T cell-mediated skin inflammation

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30 September 2017

Surfactant protein A inhibits peptidoglycan-induced tumor necrosis factor-alpha secretion in U937 cells and alveolar macrophages by direct interaction with toll-like receptor 2.

1 reference

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30 September 2017

The TNF and TNF receptor superfamilies: integrating mammalian biology

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30 September 2017

Surfactant Proteins A and D and Pulmonary Host Defense

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30 September 2017

The pulmonary collectins and surfactant metabolism

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30 September 2017

Effects of antenatal endotoxin and glucocorticoids on the lungs of preterm lambs.

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30 September 2017

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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C-type lectin-like domains

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30 September 2017

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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30 September 2017

Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D

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30 September 2017

Intraamniotic interleukin-1 accelerates surfactant protein synthesis in fetal rabbits and improves lung stability after premature birth

1 reference

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30 September 2017

Infection in the pathogenesis of preterm labor

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30 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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30 September 2017

Hormonal and developmental regulation of pulmonary surfactant synthesis in fetal lung

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30 September 2017

Structures and properties of the surfactant-associated proteins

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30 September 2017

Pulmonary surfactant protein A regulates TLR expression and activity in human macrophages

1 reference

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28 June 2018

Intra-amniotic endotoxin accelerates lung maturation in fetal rabbits.

1 reference

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28 June 2018

Accumulation of interleukin-1beta and interleukin-6 in amniotic fluid: a sequela of labour at term and preterm

1 reference

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28 June 2018

Amniotic fluid interleukin-1 in spontaneous labor at term

1 reference

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28 June 2018

Systemic administration of interleukin-1 induces preterm parturition in mice

1 reference

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28 June 2018

A study of collectin genes in spontaneous preterm birth reveals an association with a common surfactant protein D gene polymorphism.

1 reference

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21 September 2018

Interleukin-6 is an essential determinant of on-time parturition in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Intra-amniotic infection increases amniotic lamellar body count before 34 weeks of gestation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

The role of toll-like receptors (TLR-2 and -4) and triggering receptor expressed on myeloid cells 1 (TREM-1) in human term and preterm labor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 gene expression in human myometrium at labor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Innate immune function of the human decidual cell at the maternal-fetal interface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Research agenda for preterm birth: recommendations from the March of Dimes.

1 reference

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21 September 2018

New insights into the molecular endocrinology of parturition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Mechanical stretch activates type 2 cyclooxygenase via activator protein-1 transcription factor in human myometrial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Interleukin-6 is neither necessary nor sufficient for preterm labor in a murine infection model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Human labour is associated with nuclear factor-kappaB activity which mediates cyclo-oxygenase-2 expression and is involved with the 'functional progesterone withdrawal'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3529364

21 September 2018

Increased expression of the rat myometrial oxytocin receptor messenger ribonucleic acid during labor requires both mechanical and hormonal signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocytes infiltrate the myometrium during human parturition: further evidence that labour is an inflammatory process

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surfactant stimulates prostaglandin E production in human amnion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of cyclooxygenase-1 and -2 proteins in rat uterus and cervix during the estrous cycle, pregnancy, labor and in myometrial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of nuclear factor-kappa B (NF kappa B) and inhibitory factor-kappa B (I kappa B) in human fetal membranes and decidua at term and preterm delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: the immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the gap junction protein connexin-43 is increased in the human myometrium toward term and with the onset of labor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The concentration of the 35-kDa surfactant apoprotein in amniotic fluid from normal and diabetic pregnancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory cytokine mRNA in human gestational tissues: implications for term and preterm labor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reproduction in mice lacking a functional type 1 IL-1 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23183169

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/EN.2012-1797

1 reference

Europe PubMed Central

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18 February 2020

1 reference

Europe PubMed Central

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18 February 2020

1 reference

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18 February 2020

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