PVR cell adhesion molecule (Q3648605)

http://www.ebi.ac.uk/interpro/protein/P15151

Immunoglobulin-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15151

Immunoglobulin subtype, protein family

1 reference

Immunoglobulin V-set domain, protein family

1 reference

CD80-like, immunoglobulin C2-set, protein family

1 reference

immunoglobulin-like domain, protein family

1 reference

protein homodimerization activity

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

virus receptor activity

1 reference

8 April 2019

4 references

8 April 2019

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

A secreted protein microarray platform for extracellular protein interaction discovery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

signaling receptor binding

IPI

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

cell adhesion molecule binding

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

8 April 2019

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

integral component of membrane

TAS

3 references

8 April 2019

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

8 April 2019

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

26 September 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

2 references

integral component of plasma membrane

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

Mast cell costimulation by CD226/CD112 (DNAM-1/Nectin-2): a novel interface in the allergic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

IDA

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

8 April 2019

The poliovirus receptor protein is produced both as membrane-bound and secreted forms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

HDA

biological process

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

susceptibility to natural killer cell mediated cytotoxicity

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

IEA

1 reference

26 September 2017

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

regulation of immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

viral entry into host cell

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

susceptibility to T cell mediated cytotoxicity

IEA

1 reference

26 September 2017

Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15151&geneProductId=UniProtKB:P15151

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

adherens junction organization

IEA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

positive regulation of natural killer cell mediated cytotoxicity

TAS

1 reference

8 April 2019

Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

homophilic cell adhesion via plasma membrane adhesion molecules

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15151

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

susceptibility to natural killer cell mediated cytotoxicity

Identifiers

MeSH descriptor ID

C066100

subject named as

poliovirus receptor

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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13 November 2019

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016