Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism. (Q36481794)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115239%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism (English)

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16 February 2020

3

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16 February 2020

David M Maclean

4

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16 February 2020

author name string

Swarna Ramaswamy

1

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16 February 2020

David Cooper

2

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16 February 2020

Anu Rambhadran

5

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16 February 2020

J Nick Taylor

6

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16 February 2020

Heui Uhm

7

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16 February 2020

Christy F Landes

8

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16 February 2020

Vasanthi Jayaraman

9

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16 February 2020

language of work or name

English

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publication date

31 October 2012

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Journal of Biological Chemistry

16 February 2020

published in

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16 February 2020

volume

287

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16 February 2020

issue

52

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16 February 2020

page(s)

43557-43564

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Mechanism of AMPA Receptor Activation by Partial Agonists: DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS

16 February 2020

cites work

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Cations but not anions regulate the responsiveness of kainate receptors.

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Structural landscape of isolated agonist-binding domains from single AMPA receptors

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Role of dimer interface in activation and desensitization in AMPA receptors

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Hydrophobic side chain dynamics of a glutamate receptor ligand binding domain

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Enhanced Efficacy without Further Cleft Closure: Reevaluating Twist as a Source of Agonist Efficacy in AMPA Receptors

30 September 2017

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Denoising single-molecule FRET trajectories with wavelets and Bayesian inference

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X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

30 September 2017

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Mechanisms of Antagonism of the GluR2 AMPA Receptor: Structure and Dynamics of the Complex of Two Willardiine Antagonists with the Glutamate Binding Domain

30 September 2017

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Structure of the S1S2 glutamate binding domain of GLuR3

30 September 2017

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Human T-cell lymphotropic virus type 1 nucleocapsid protein-induced structural changes in transactivation response DNA hairpin measured by single-molecule fluorescence resonance energy transfer

30 September 2017

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Mechanism of partial agonism at the GluR2 AMPA receptor: Measurements of lobe orientation in solution

30 September 2017

1 reference

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LRET investigations of conformational changes in the ligand binding domain of a functional AMPA receptor

30 September 2017

1 reference

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Dynamics of an anti-VEGF DNA aptamer: a single-molecule study

30 September 2017

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NMR spectroscopy of the ligand-binding core of ionotropic glutamate receptor 2 bound to 5-substituted willardiine partial agonists

30 September 2017

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Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating

30 September 2017

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Chemical interplay in the mechanism of partial agonist activation in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

30 September 2017

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Glutamate receptors as seen by light: spectroscopic studies of structure-function relationships

30 September 2017

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30 September 2017

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The cell biology of synaptic plasticity: AMPA receptor trafficking

30 September 2017

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AMPA receptor potentiators: application for depression and Parkinson's disease

30 September 2017

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30 September 2017

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Allosteric mechanism in AMPA receptors: a FRET-based investigation of conformational changes

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

30 September 2017

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The structure and function of glutamate receptor ion channels

30 September 2017

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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

30 September 2017

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Structure of a glutamate-receptor ligand-binding core in complex with kainate

30 September 2017

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Molecular diversity and functions of glutamate receptors

30 September 2017

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Modulation of AMPA receptor function in relation to glutamatergic abnormalities in Alzheimer's disease

30 September 2017

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Glutamate receptor channels: novel properties and new clones

30 September 2017

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Molecular diversity of glutamate receptors and implications for brain function

30 September 2017

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Improved resolution of complex single-molecule FRET systems via wavelet shrinkage.

30 September 2017

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Evolution of glutamate interactions during binding to a glutamate receptor

21 September 2018

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Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.

21 September 2018

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Spectroscopic and kinetic methods for ligand-protein interactions of glutamate receptor

21 September 2018

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Structural mobility of the extracellular ligand-binding core of an ionotropic glutamate receptor. Analysis of NMR relaxation dynamics

21 September 2018

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Stereochemistry of quinoxaline antagonist binding to a glutamate receptor investigated by Fourier transform infrared spectroscopy.

21 September 2018

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Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning.

21 September 2018

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Fourier transform infrared spectroscopic characterization of a photolabile precursor of glutamate

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23115239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamics of the S1S2 glutamate binding domain of GluR2 measured using 19F NMR spectroscopy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23115239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ligand--protein interactions in the glutamate receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23115239

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.371815

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115239%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23115239%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference