Targeted therapy for short QT syndrome (Q36481056)

14 August 2017

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title

Targeted therapy for short QT syndrome (English)

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14 August 2017

Preben Bjerregaard

1

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14 August 2017

Arshad Jahangir

series ordinal

2

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14 August 2017

Ihor Gussak

series ordinal

3

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14 August 2017

language of work or name

English

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publication date

1 June 2006

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Expert Opinion on Therapeutic Targets

14 August 2017

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14 August 2017

10

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14 August 2017

3

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14 August 2017

393-400

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Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval and sudden death

14 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Short QT syndrome: mechanisms, diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

A novel form of short QT syndrome (SQT3) is caused by a mutation in the KCNJ2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Short QT Syndrome: a familial cause of sudden death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Sudden death associated with short-QT syndrome linked to mutations in HERG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Clinical characteristics and treatment of short QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Short QT syndrome: successful prevention of sudden cardiac death in an adolescent by implantable cardioverter-defibrillator treatment for primary prophylaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Short QT syndrome: pharmacological treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

The voltage-gated potassium channels and their relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Modulation of I(Kr) inactivation by mutation N588K in KCNH2: a link to arrhythmogenesis in short QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

The N588K-HERG K+ channel mutation in the 'short QT syndrome': mechanism of gain-in-function determined at 37 degrees C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Inhibition of HERG potassium channel current by the class 1a antiarrhythmic agent disopyramide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Principles of selective ion transport in channels and pumps

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Structural determinants and biophysical properties of HERG and KCNQ1 channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Refining detection of drug-induced proarrhythmia: QT interval and TRIaD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Stilbenes and fenamates rescue the loss of I(KS) channel function induced by an LQT5 mutation and other IsK mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

In vivo antiarrhythmic and cardiac electrophysiologic effects of a novel diphenylphosphine oxide IKur blocker (2-isopropyl-5-methylcyclohexyl) diphenylphosphine oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

K(ATP) channel therapeutics at the bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Proarrhythmia as a pharmacogenomic entity: a critical review and formulation of a unifying hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

New approaches to antiarrhythmic therapy; emerging therapeutic applications of the cell biology of cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Idiopathic short QT interval: a new clinical syndrome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Antisense oligodeoxynucleotides directed against Kv1.5 mRNA specifically inhibit ultrarapid delayed rectifier K+ current in cultured adult human atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

Gene delivery to cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.10.3.393

10.1517/14728222.10.3.393

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference