Subcellular remodeling as a viable target for the treatment of congestive heart failure (Q36480082)

14 August 2017

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title

Subcellular remodeling as a viable target for the treatment of congestive heart failure (English)

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14 August 2017

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congestive heart failure

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Naranjan S Dhalla

1

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14 August 2017

Melissa R Dent

2

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14 August 2017

Paramjit S Tappia

3

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14 August 2017

Rajat Sethi

4

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14 August 2017

Judit Barta

5

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14 August 2017

Ramesh K Goyal

6

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14 August 2017

1 March 2006

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Journal of Cardiovascular Pharmacology and Therapeutics

14 August 2017

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14 August 2017

11

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14 August 2017

31-45

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14 August 2017

1

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The molecular and cellular pathophysiology of heart failure.

14 August 2017

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https://api.crossref.org/works/10.1177%2F107424840601100103

21 January 2018

The failing human heart

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https://api.crossref.org/works/10.1177%2F107424840601100103

Cardiac remodeling--concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Role of oxidative stress in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Animal models of human cardiovascular disease, heart failure and hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Highlights on endothelins: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Molecular mechanisms of myocardial remodeling. The role of aldosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Structural remodeling in hypertensive heart disease and the role of hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The Neurohumoral Axis in Congestive Heart Failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Ventricular remodelling: consequences and therapy

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Significance of matrix metalloproteinases in norepinephrine-induced remodelling of rat hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Ultrastructure and calcium exchange of the sarcolemma, sarcoplasmic reticulum and mitochondria of the myocardium

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

The homeostasis of calcium in heart cells

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Subcellular basis of cardiac contractile failure

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Calcium movements in relation to heart function

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Cellular mechanisms of contractile dysfunction in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Signaling pathways in cardiac myocyte hypertrophy

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Altered calcium handling in left ventricular pressure-overload hypertrophy as detected with aequorin in the isolated, perfused ferret heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Intracellular calcium transients in myocardium from spontaneously hypertensive rats during the transition to heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Depressed intracellular calcium transients and contraction in myocytes from hypertrophied and failing guinea pig hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Diminished post-rest potentiation of contractile force in human dilated cardiomyopathy. Functional evidence for alterations in intracellular Ca2+ handling

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Impaired Ca2+ handling is an early manifestation of pressure-overload hypertrophy in rat hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Calcium sequestration by the sarcoplasmic reticulum in heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)-ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Heterogeneous transmural gene expression of calcium-handling proteins and natriuretic peptides in the failing human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Elevated sarcoplasmic reticulum Ca2+ leak in intact ventricular myocytes from rabbits in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The Na, K-ATPase in the failing human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Intracellular Na+ and altered Na+ transport mechanisms in cardiac hypertrophy and failure

21 January 2018

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https://api.crossref.org/works/10.1177%2F107424840601100103

Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Increased exchange current but normal Ca2+ transport via Na+-Ca2+ exchange during cardiac hypertrophy after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Immunologic identification of Na+,K(+)-ATPase isoforms in myocardium. Isoform change in deoxycorticosterone acetate-salt hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Hypokalemia decreases Na(+)-K(+)-ATPase alpha 2- but not alpha 1-isoform abundance in heart, muscle, and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Stereoselective electrophysiological effects of propafenone in Langendorff perfused guinea pig hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Reduced calcium current density in single myocytes isolated from hypertrophied failing guinea pig hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The effects of compensated cardiac hypertrophy on dihydropyridine and ryanodine receptors in rat, ferret and guinea-pig hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Myosin heavy chain synthesis is increased in a rabbit model of heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Contractile and cytoskeletal content, structure, and mRNA levels with tachycardia-induced cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Control of beta-myosin heavy chain expression in systemic hypertension and caloric restriction in the rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Changes in essential myosin light chain isoform expression provide a molecular basis for isometric force regulation in the failing human heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Molecular basis of human cardiac troponin T isoforms expressed in the developing, adult, and failing heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Human cardiac troponin T: cloning and expression of new isoforms in the normal and failing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Molecular cloning of human cardiac troponin T isoforms: expression in developing and failing heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Maximal ATPase activity and calcium sensitivity of reconstituted myofilaments are unaltered by the fetal troponin T re-expressed during human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The cardiac renin-angiotensin system: conceptual, or a regulator of cardiac function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Renin-angiotensin system, hypertrophy and gene expression in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The cardiac renin-angiotensin system: novel signaling mechanisms related to cardiac growth and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Thyroxine-induced cardiac hypertrophy: influence of adrenergic nervous system versus renin-angiotensin system on myocyte remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Modification of beta-adrenoceptor signal transduction pathway by genetic manipulation and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Phorbol myristate acetate-induced hypertrophy of neonatal rat cardiac myocytes is associated with decreased sarcoplasmic reticulum Ca2+ ATPase (SERCA2) gene expression and calcium reuptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Pharmacological inhibitors of MAPK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The ups and downs of MEK kinase interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Stress-activated protein kinases in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Cardiac failure in coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Morphometric mapping of regional myocyte diameters after healing of myocardial infarction in cats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Left ventricular shape changes during the course of evolving heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Biomechanical properties of reperfused transmural myocardial infarcts in rabbits during the first week after infarction. Implications for left ventricular rupture

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Rapid expression of fibronectin in the rabbit heart after myocardial infarction with and without reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Myocardial infarct size and ventricular function in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Regulation of K+ and Ca2+ channels in experimental cardiac failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Myocardial infarction in rats. Infarct size, myocyte hypertrophy, and capillary growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Changes in heart function and cardiac cell size in rats with chronic myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Myocardial infarction and regulatory myosin light chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Right ventricular contractile protein function in rats with left ventricular myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Induction of myocardial hypertrophy after coronary ligation in rats decreases ventricular dilatation and improves systolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Differential changes in sympathetic activity in left and right ventricles in congestive heart failure after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Vasodilatory action of endogenous atrial natriuretic factor in a rat model of chronic heart failure as determined by monoclonal ANF antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Nitrendipine binding in congestive heart failure due to myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Electrophysiological properties of mechanosensitive atrial fibroblasts from chronic infarcted rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Calcium currents in postinfarction rat cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Effect of ramipril and losartan on collagen expression in right and left heart after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Hormonal and cardiac effects of converting enzyme inhibition in rat myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Survival after myocardial infarction in the rat. Role of tissue angiotensin-converting enzyme inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Long-term treatment with angiotensin I-converting enzyme inhibitors attenuates the loss of cardiac beta-adrenoceptor responses in rats with chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Long-term effects of beta-adrenergic blocking agent treatment on hemodynamic function and left ventricular remodeling in rats with experimental myocardial infarction: importance of timing of treatment and infarct size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Beta-blockers in heart failure. Future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris. Results of the International Multicenter Angina Exercise (IMAGE) Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Outcome with calcium channel antagonists after myocardial infarction: a community-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

A double-blind, placebo-controlled crossover trial of nadolol and verapamil in mild and moderately symptomatic hypertrophic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Favorable left ventricular remodeling following large myocardial infarction by exercise training. Effect on ventricular morphology and gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Effects of quinapril, losartan and hydralazine on cardiac hypertrophy and beta-adrenergic neuroeffector mechanisms in transgenic (mREN2)27 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Alterations of adenylyl cyclase and G proteins in aortocaval shunt-induced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Upregulation of beta-adrenergic receptors in heart failure due to volume overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Depressed responsiveness of phospholipase C isoenzymes to phosphatidic acid in congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Imidapril treatment improves the attenuated inotropic and intracellular calcium responses to ATP in heart failure due to myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Sarcoplasmic reticulum Ca2+ transport and gene expression in congestive heart failure are modified by imidapril treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Modification of sarcolemmal Na+-K+-ATPase and Na+/Ca2+ exchanger expression in heart failure by blockade of renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Influence of long-term treatment of imidapril on mortality, cardiac function, and gene expression in congestive heart failure due to myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Changes in beta-adrenoceptors in heart failure due to myocardial infarction are attenuated by blockade of renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Prevention of remodeling in congestive heart failure due to myocardial infarction by blockade of the renin-angiotensin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Abnormalities of calcium cycling in the hypertrophied and failing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Improvement of cardiac function and beta-adrenergic signal transduction by propionyl L-carnitine in congestive heart failure due to myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Na(+)/H(+) exchange inhibition reduces hypertrophy and heart failure after myocardial infarction in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Effect of AT1 receptor blockade on cardiac collagen remodeling after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Altered mRNA Abundance of Calcium Transport Genes in Cardiac Myocytes Induced by Angiotensin II

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Alteration of collagenous protein profile in congestive heart failure secondary to myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

Modification of the extracellular matrix following myocardial infarction monitored by FTIR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107424840601100103

10.1177/107424840601100103

21 January 2018

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DOI

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14 August 2017

1 reference