The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival (Q36477263)

14 August 2017

The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival (English)

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14 August 2017

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Wendy M McKimpson

1

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14 August 2017

Jeremy Weinberger

2

1 reference

14 August 2017

Lech Czerski

3

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14 August 2017

Min Zheng

4

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14 August 2017

Michael T Crow

5

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14 August 2017

Jeffrey E Pessin

6

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14 August 2017

Streamson C Chua

7

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14 August 2017

Richard N Kitsis

8

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14 August 2017

language of work or name

English

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publication date

29 August 2012

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14 August 2017

11

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inferred from page(s)

published in

Diabetes

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14 August 2017

62

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14 August 2017

183-193

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14 August 2017

1

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

14 August 2017

start time

27 August 2021

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3526036/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension

30 September 2017

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Apoptosis inhibitor ARC promotes breast tumorigenesis, metastasis, and chemoresistance

30 September 2017

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Endoplasmic reticulum stress, obesity and diabetes

30 September 2017

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Endoplasmic reticulum oxidoreductin-1-like β (ERO1lβ) regulates susceptibility to endoplasmic reticulum stress and is induced by insulin flux in β-cells

30 September 2017

1 reference

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Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity

30 September 2017

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

30 September 2017

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Signaling cell death from the endoplasmic reticulum stress response

30 September 2017

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Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML

30 September 2017

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Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity

30 September 2017

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Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

30 September 2017

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Mitochondria and cell death: outer membrane permeabilization and beyond

30 September 2017

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Induction of the apoptosis inhibitor ARC by Ras in human cancers

30 September 2017

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Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death

30 September 2017

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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes

30 September 2017

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Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice

30 September 2017

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Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

30 September 2017

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ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer

30 September 2017

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The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes

30 September 2017

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Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein

30 September 2017

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Regulation of p53 tetramerization and nuclear export by ARC

30 September 2017

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The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients.

30 September 2017

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Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes

30 September 2017

1 reference

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The apoptosis inhibitor ARC undergoes ubiquitin-proteasomal-mediated degradation in response to death stimuli: identification of a degradation-resistant mutant

30 September 2017

1 reference

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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

30 September 2017

1 reference

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Islet beta cell failure in type 2 diabetes

30 September 2017

1 reference

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Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

30 September 2017

1 reference

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Apoptosis repressor with caspase recruitment domain (ARC) is expressed in cancer cells and localizes to nuclei

30 September 2017

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

30 September 2017

1 reference

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Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions

30 September 2017

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Apoptosis repressor with caspase recruitment domain protects against cell death by interfering with Bax activation

30 September 2017

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Cell death: critical control points

30 September 2017

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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

30 September 2017

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The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

30 September 2017

1 reference

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Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Functional analysis of a conditionally transformed pancreatic beta-cell line

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Cloning and characterization of cDNAs for novel proteins with glutamic acid-proline dipeptide tandem repeats

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

ARC, an apoptosis suppressor limited to terminally differentiated cells, is induced in human breast cancer and confers chemo- and radiation-resistance.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3526036

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models

21 September 2018

1 reference

12 December 2020

Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion

1 reference

12 December 2020

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

1 reference

12 December 2020

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB12-0504

1 reference

14 August 2017

1 reference

14 August 2017

1 reference