High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE (Q36464675)

14 August 2017

High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE (English)

1 reference

genome-wide association study

14 August 2017

0 references

16

Gail P Jarvik

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Jennifer A Pacheco

Jennifer A Pacheco

2

0 references

Catherine A. McCarty

Catherine A McCarty

20

0 references

Marylyn D. Ritchie

5

Marylyn D Ritchie

1 reference

14 August 2017

23

Dana C Crawford

1 reference

14 August 2017

Teri A Manolio

22

0 references

Joshua C. Denny

15

Joshua C Denny

1 reference

14 August 2017

Laura J Rasmussen-Torvik

1

Laura J Rasmussen-Torvik

1 reference

14 August 2017

14

Dan M Roden

1 reference

14 August 2017

24

Rex L Chisholm

1 reference

14 August 2017

3

Russell A Wilke

1 reference

14 August 2017

6

Abel N Kho

1 reference

14 August 2017

9

Loren L Armstrong

1 reference

14 August 2017

12

Rebecca L Zuvich

1 reference

14 August 2017

13

David Crosslin

1 reference

14 August 2017

18

Iftikhar J Kullo

1 reference

14 August 2017

19

Suzette J Bielinski

1 reference

14 August 2017

William K Thompson

4

1 reference

14 August 2017

Arun Muthalagu

7

1 reference

14 August 2017

M Geoff Hayes

8

1 reference

14 August 2017

Douglas A Scheftner

10

1 reference

14 August 2017

John T Wilkins

11

1 reference

14 August 2017

Christopher S Carlson

17

1 reference

14 August 2017

Rongling Li

21

1 reference

14 August 2017

language of work or name

English

0 references

publication date

23 August 2012

1 reference

Clinical and Translational Science

14 August 2017

1 reference

14 August 2017

5

1 reference

14 August 2017

394-399

1 reference

14 August 2017

5

1 reference

Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Complement receptor 1 gene variants are associated with erythrocyte sedimentation rate

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Electronic medical records for genetic research: results of the eMERGE consortium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Quality control procedures for genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Identification of genomic predictors of atrioventricular conduction: using electronic medical records as a tool for genome science

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Leveraging informatics for genetic studies: use of the electronic medical record to enable a genome-wide association study of peripheral arterial disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Biological, clinical and population relevance of 95 loci for blood lipids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

APOE is not associated with Alzheimer disease: a cautionary tale of genotype imputation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination Survey

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Common variants at 30 loci contribute to polygenic dyslipidemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Association of apolipoprotein E genotypes with lipid levels and coronary risk

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

PLINK: a tool set for whole-genome association and population-based linkage analyses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Population structure and eigenanalysis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Principal components analysis corrects for stratification in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

The role of apolipoprotein E genetic variants in lipoprotein disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521536

Apolipoprotein E polymorphism and atherosclerosis

30 September 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23067351

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1752-8062.2012.00446.X

1 reference

14 August 2017

1 reference

14 August 2017

1 reference