Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects (Q36458384)

14 August 2017

1 reference

title

Methylnaltrexone, a novel peripheral opioid receptor antagonist for the treatment of opioid side effects (English)

1 reference

14 August 2017

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Chun-Su Yuan

1

1 reference

PubMed ID

16634692

14 August 2017

Robert J Israel

series ordinal

2

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PubMed ID

16634692

14 August 2017

language of work or name

English

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publication date

1 May 2006

1 reference

Expert Opinion on Investigational Drugs

14 August 2017

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14 August 2017

15

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14 August 2017

5

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14 August 2017

541-552

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Managing your patients' adverse reactions to narcotics

14 August 2017

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Unrecognized constipation in patients with advanced cancer: a recipe for therapeutic disaster

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Naloxone infusion after prophylactic epidural morphine: effects on incidence of postoperative side-effects and quality of analgesia.

21 January 2018

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Treatment of opioid-induced constipation with oral naloxone: A pilot study

21 January 2018

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Assessment of nalmefene glucuronide as a selective gut opioid antagonist.

21 January 2018

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The use of quaternary narcotic antagonists in opiate research

21 January 2018

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Antagonism of gut, but not central effects of morphine with quaternary narcotic antagonists

21 January 2018

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Variations in demethylation of N-methylnaltrexone in mice, rats, dogs, and humans

21 January 2018

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Role of central versus peripheral opioid receptors in analgesia induced by repeated administration of opioid antagonists

21 January 2018

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Gastric effects of mu-, delta- and kappa-opioid receptor agonists on brainstem unitary responses in the neonatal rat.

21 January 2018

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Gastric effects of methylnaltrexone on mu, kappa, and delta opioid agonists induced brainstem unitary responses

21 January 2018

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The central and peripheral influences of opioids on gastrointestinal propulsion

21 January 2018

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Effects of methylnaltrexone on morphine-induced inhibition of contraction in isolated guinea-pig ileum and human intestine

21 January 2018

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21 January 2018

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Methylnaltrexone prevents morphine-induced kaolin intake in the rat.

21 January 2018

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Safety and tolerance of methylnaltrexone in healthy humans: a randomized, placebo-controlled, intravenous, ascending-dose, pharmacokinetic study.

21 January 2018

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Tolerability, gut effects, and pharmacokinetics of methylnaltrexone following repeated intravenous administration in humans

21 January 2018

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Determination of methylnaltrexone in clinical samples by solid-phase extraction and high-performance liquid chromatography for a pharmacokinetics study

21 January 2018

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Methylnaltrexone prevents morphine-induced delay in oral-cecal transit time without affecting analgesia: a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

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Effects of subcutaneous methylnaltrexone on morphine-induced peripherally mediated side effects: a double-blind randomized placebo-controlled trial

21 January 2018

1 reference

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The safety and efficacy of oral methylnaltrexone in preventing morphine-induced delay in oral-cecal transit time.

21 January 2018

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Effects of enteric-coated methylnaltrexone in preventing opioid-induced delay in oral-cecal transit time

21 January 2018

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Efficacy of methylnaltrexone versus naloxone for reversal of morphine-induced depression of hypoxic ventilatory response.

21 January 2018

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Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbable carbohydrate

21 January 2018

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21 January 2018

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Effects of low-dose morphine on gastric emptying in healthy volunteers.

21 January 2018

1 reference

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Opioid-induced delay in gastric emptying: a peripheral mechanism in humans

21 January 2018

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Gut motility and transit changes in patients receiving long-term methadone maintenance.

21 January 2018

1 reference

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Effects of intravenous methylnaltrexone on opioid-induced gut motility and transit time changes in subjects receiving chronic methadone therapy: a pilot study

21 January 2018

1 reference

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Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial.

21 January 2018

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Oral methylnaltrexone for opioid-induced constipation

21 January 2018

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Improving palliative care

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Mechanisms of postoperative ileus

21 January 2018

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A clinical pathway to accelerate recovery after colonic resection

21 January 2018

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Opioids and opioid receptors in the enteric nervous system: from a problem in opioid analgesia to a possible new prokinetic therapy in humans

21 January 2018

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Naloxone, a specific opioid antagonist, reverses chronic idiopathic constipation

21 January 2018

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Naloxone treatment for irritable bowel syndrome--a randomized controlled trial with an oral formulation

21 January 2018

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Effects of codeine, morphine and a novel opioid pentapeptide BW443C, on cough, nociception and ventilation in the unanaesthetized guinea-pig

21 January 2018

1 reference

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Effects of methylnaltrexone on morphine-induced cough suppression in guinea pigs

21 January 2018

1 reference

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Urinary retention during i.m. and extradural morphine analgesia

21 January 2018

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Opioid-induced immunosuppression: is it centrally mediated or peripherally mediated?

21 January 2018

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Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations

21 January 2018

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Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytes

21 January 2018

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Opiates, mast cells and histamine release

21 January 2018

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In vitro evaluation of the potential role of sulfite radical in morphine-associated histamine release

21 January 2018

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Efficacy of orally administered methylnaltrexone in decreasing subjective effects after intravenous morphine.

21 January 2018

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21 January 2018

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10.1517/13543784.15.5.541

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16634692