The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development (Q36446371)

14 August 2017

The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development (English)

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14 August 2017

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Changhui Ge

1

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14 August 2017

Pamela Stanley

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

28 January 2008

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

105

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14 August 2017

1539-1544

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14 August 2017

5

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describes a project that uses

14 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2234180/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Presenilins regulate alphabeta T cell development by modulating TCR signaling

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The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling

30 September 2017

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The requirement for Notch signaling at the beta-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor.

30 September 2017

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30 September 2017

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Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

30 September 2017

1 reference

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Notch signaling in hematopoiesis and lymphopoiesis: lessons from Drosophila.

30 September 2017

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

30 September 2017

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Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

30 September 2017

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The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

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Cre-mediated germline mosaicism: a new transgenic mouse for the selective removal of residual markers from tri-lox conditional alleles

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Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region

30 September 2017

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The role of Notch signaling during hematopoietic lineage commitment

30 September 2017

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Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

30 September 2017

1 reference

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Fringe is a glycosyltransferase that modifies Notch

30 September 2017

1 reference

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Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

30 September 2017

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Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

30 September 2017

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Cutting edge: protective effects of notch-1 on TCR-induced apoptosis.

30 September 2017

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Correlating notch signaling with thymocyte maturation

30 September 2017

1 reference

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Notch1 is required for the coordinate segmentation of somites

30 September 2017

1 reference

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WW6: an embryonic stem cell line with an inert genetic marker that can be traced in chimeras

30 September 2017

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Highly conserved O-fucose sites have distinct effects on Notch1 function

30 September 2017

1 reference

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Notch receptor activation inhibits oligodendrocyte differentiation.

28 June 2018

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Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen

28 June 2018

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Notch1 is essential for postimplantation development in mice.

28 June 2018

1 reference

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Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

28 June 2018

1 reference

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Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

An O-fucose site in the ligand binding domain inhibits Notch activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats

21 January 2018

1 reference

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Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Notch1-induced transformation of RKE-1 cells requires up-regulation of cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

The Notch regulator Numb links the Notch and TCR signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

21 January 2018

1 reference

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Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702846105

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18227520

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0702846105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

1 reference