Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy. (Q36444286)

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scientific article published in May 2006

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English	Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy.	scientific article published in May 2006

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scholarly article

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19 January 2020

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Europe PubMed Central

Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16603723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Naibedya Chattopadhyay

1

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19 January 2020

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Naibedya Chattopadhyay

1

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14 August 2017

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1 May 2006

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19 January 2020

American Journal of Physiology - Endocrinology and Metabolism

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19 January 2020

290

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19 January 2020

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19 January 2020

E761-70

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19 January 2020

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

1 reference

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Interaction of the calcium-sensing receptor and filamin, a potential scaffolding protein

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In vivo and in vitro characterization of neonatal hyperparathyroidism resulting from a de novo, heterozygous mutation in the Ca2+-sensing receptor gene: normal maternal calcium homeostasis as a cause of secondary hyperparathyroidism in familial [...]

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Protein kinase C phosphorylation of threonine at position 888 in Ca2+o-sensing receptor (CaR) inhibits coupling to Ca2+ store release

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Changes in calcium responsiveness and handling during keratinocyte differentiation. Potential role of the calcium receptor

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Phosphatidylinositol 3-kinase-dependent, MEK- independent proliferation in response to CaR activation

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Localization of the extracellular Ca(2+)-sensing receptor in the human placenta.

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Calcium-stimulated parathyroid hormone-like protein secretion: potentiation through a protein kinase-C pathway

1 reference

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Calcium sensing receptors as integrators of multiple metabolic signals

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Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

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Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression.

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Mitogenic action of calcium-sensing receptor on rat calvarial osteoblasts

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Parathyroid hormone-related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the pancreatic islets.

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Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones

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EGFR signal transactivation in cancer cells

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Parathyroid hormone and parathyroid hormone-related peptide, and their receptors

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Calcimimetic agents for the treatment of secondary hyperparathyroidism

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21 January 2018

Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysis

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Alveolar epithelial cells express and secrete parathyroid hormone-related protein

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

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Epidermal growth factor-stimulated parathyroid hormone-related protein expression involves increased gene transcription and mRNA stability

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

21 January 2018

Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

21 January 2018

A mouse model of human familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

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21 January 2018

Signal transduction mechanisms linking increased extracellular calcium to proliferation in ovarian surface epithelial cells.

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Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification

1 reference

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21 January 2018

Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function

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21 January 2018

Extracellular calcium downregulates estrogen receptor alpha and increases its transcriptional activity through calcium-sensing receptor in breast cancer cells

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Mechanisms of osteolytic bone metastases in breast carcinoma

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Transforming growth factor-beta stimulates parathyroid hormone-related protein and osteolytic metastases via Smad and mitogen-activated protein kinase signaling pathways

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Calcium-dependent c-myc proto-oncogene expression and proliferation of Caco-2 cells: a role for a luminal extracellular calcium-sensing receptor

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21 January 2018

Prostate cancer bone metastases promote both osteolytic and osteoblastic activity

1 reference

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21 January 2018

Regulation of protein kinase C by extracellular calcium in bovine parathyroid cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

21 January 2018

Epidermal expression of the full-length extracellular calcium-sensing receptor is required for normal keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

21 January 2018

Calcium and bone metabolism during pregnancy and lactation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

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Regulation of murine fetal-placental calcium metabolism by the calcium-sensing receptor

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Role of nitric oxide in carcinogenesis and tumour progression

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Importin beta recognizes parathyroid hormone-related protein with high affinity and mediates its nuclear import in the absence of importin alpha

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

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Phosphorylation at the cyclin-dependent kinases site (Thr85) of parathyroid hormone-related protein negatively regulates its nuclear localization

1 reference

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Elevated extracellular calcium can prevent apoptosis via the calcium-sensing receptor.

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Ets2 and protein kinase C epsilon are important regulators of parathyroid hormone-related protein expression in MCF-7 breast cancer cells

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Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

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PTHrP stimulated by the calcium-sensing receptor requires MAP kinase activation

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Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism

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Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium

1 reference

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21 January 2018

Functional calcium-sensing receptor expression in ovarian surface epithelial cells.

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p38 MAP kinases: beyond the stress response

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Calcimimetics with potent and selective activity on the parathyroid calcium receptor

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Cinacalcet hydrochloride maintains long-term normocalcemia in patients with primary hyperparathyroidism

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Mutations in the human Ca(2+)-sensing receptor gene cause familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00350.2005

21 January 2018

Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutation

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Extracellular calcium-sensing receptor (CaR) expression and its potential role in parathyroid hormone-related peptide (PTHrP) secretion in the H-500 rat Leydig cell model of humoral hypercalcemia of malignancy.

1 reference

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Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion

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Parathyroid hormone-related protein enhances PC-3 prostate cancer cell growth via both autocrine/paracrine and intracrine pathways

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Biochemical evaluation of patients with cancer-associated hypercalcemia: evidence for humoral and nonhumoral groups.

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A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression

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Calcium-sensing receptor induces proliferation through p38 mitogen-activated protein kinase and phosphatidylinositol 3-kinase but not extracellularly regulated kinase in a model of humoral hypercalcemia of malignancy

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Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells

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Calcium-sensing receptor induces messenger ribonucleic acid of human securin, pituitary tumor transforming gene, in rat testicular cancer.

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The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor

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Calcium receptor-mediated intracellular signalling

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Mouse osteoblastic cell line (MC3T3-E1) expresses extracellular calcium (Ca2+o)-sensing receptor and its agonists stimulate chemotaxis and proliferation of MC3T3-E1 cells

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Identifiers

10.1152/AJPENDO.00350.2005

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16603723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16603723%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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