BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance (Q36432043)

14 August 2017

BMI1 induces an invasive signature in melanoma that promotes metastasis and chemoresistance (English)

1 reference

14 August 2017

Roberta Ferretti

1

1 reference

14 August 2017

Arjun Bhutkar

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2

1 reference

14 August 2017

Molly C McNamara

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3

1 reference

14 August 2017

Jacqueline A Lees

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4

1 reference

14 August 2017

17 December 2015

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14 August 2017

1 reference

14 August 2017

30

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14 August 2017

1

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14 August 2017

18-33

1 reference

describes a project that uses

14 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4701976

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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MITF Modulates Therapeutic Resistance through EGFR Signaling

30 September 2017

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Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

30 September 2017

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Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond

30 September 2017

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WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors.

30 September 2017

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PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation

30 September 2017

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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

30 September 2017

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Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

30 September 2017

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The ZEB1 transcription factor acts in a negative feedback loop with miR200 downstream of Ras and Rb1 to regulate Bmi1 expression

30 September 2017

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Bmi1 is required for tumorigenesis in a mouse model of intestinal cancer

30 September 2017

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The small GTPase ARF6 stimulates β-catenin transcriptional activity during WNT5A-mediated melanoma invasion and metastasis

30 September 2017

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30 September 2017

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Chromosome instability modulated by BMI1-AURKA signaling drives progression in head and neck cancer

30 September 2017

1 reference

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Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus

30 September 2017

1 reference

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miR-200c inhibits melanoma progression and drug resistance through down-regulation of BMI-1.

30 September 2017

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PHF19 and Akt control the switch between proliferative and invasive states in melanoma

30 September 2017

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β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas

30 September 2017

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The Akt signaling pathway: an emerging therapeutic target in malignant melanoma.

30 September 2017

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

30 September 2017

1 reference

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Proinvasion metastasis drivers in early-stage melanoma are oncogenes

30 September 2017

1 reference

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MiR-200b and miR-15b regulate chemotherapy-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting BMI1.

30 September 2017

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In melanoma, beta-catenin is a suppressor of invasion.

30 September 2017

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FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells

30 September 2017

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Polycomb group proteins in the DNA damage response: a link between radiation resistance and "stemness".

30 September 2017

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

30 September 2017

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

30 September 2017

1 reference

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Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition

30 September 2017

1 reference

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Cancer stem cells versus phenotype-switching in melanoma

30 September 2017

1 reference

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A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers

30 September 2017

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Integrative genome comparison of primary and metastatic melanomas

30 September 2017

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

30 September 2017

1 reference

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The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

30 September 2017

1 reference

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The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

30 September 2017

1 reference

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Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

30 September 2017

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Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

30 September 2017

1 reference

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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

30 September 2017

1 reference

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Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

In vivo switching of human melanoma cells between proliferative and invasive states

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Metastasis: a question of life or death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

The WNT/Beta-catenin pathway in melanoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Microarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Stem cells and cancer; the polycomb connection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Bmi1, stem cells, and senescence regulation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Mutations of the BRAF gene in human cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Selection of Successive Tumour Lines for Metastasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Systematic classification of melanoma cells by phenotype-specific gene expression mapping.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

Loss of BMI-1 expression is associated with clinical progress of malignant melanoma.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4701976

21 September 2018

Identifiers

DOI

10.1101/GAD.267757.115

1 reference

14 August 2017

1 reference

14 August 2017

1 reference