Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism (Q36424540)

14 August 2017

1 reference

title

Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism (English)

1 reference

14 August 2017

1 reference

parkinsonian syndrome

1 reference

1

Anette Schrag

1 reference

14 August 2017

Jonathan M Schott

2

1 reference

14 August 2017

1 April 2006

1 reference

14 August 2017

1 reference

14 August 2017

5

1 reference

14 August 2017

4

1 reference

14 August 2017

355-363

1 reference

Cross sectional prevalence survey of idiopathic Parkinson's disease and Parkinsonism in London

14 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Young onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Environmental antecedents of young-onset Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Young-onset Parkinson's disease: a clinical review

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Diagnostic considerations in juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Young-onset Parkinson's disease revisited--clinical features, natural history, and mortality

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Familial juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Multicenter genetic study of retinitis pigmentosa in Japan: II. Prevalence of autosomal recessive retinitis pigmentosa

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A recent survey of consanguineous marriages in Japan

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

An expected decrease in the incidence of autosomal recessive disease due to decreasing consanguineous marriages

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Association between early-onset Parkinson's disease and mutations in the parkin gene

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Huntington's disease and other choreas.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

New pathologic observations in juvenile onset parkinsonism with dystonia.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Parkinson disease in twins: an etiologic study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Sporadic rapid-onset dystonia-parkinsonism presenting as Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

When Is Ataxia Not Ataxia?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Progressive supranuclear palsy: where are we now?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Multiple system atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Corticobasal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Consensus statement on the diagnosis of multiple system atrophy.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Progression of motor impairment and disability in Parkinson disease: a population-based study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Onset and progression of disease in familial and sporadic Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Paroxysmal exercise-induced dystonia as a presenting feature of young-onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A comparison of clinical and pathological features of young- and old-onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Young-onset Parkinson disease with and without parkin gene mutations: a fluorodopa F 18 positron emission tomography study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Normal dopamine transporter binding in dopa responsive dystonia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Genetics of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical and pathological features of a parkinsonian syndrome in a family with an Ala53Thr ?-synuclein mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

PET studies of parkinsonism associated with mutation in the alpha-synuclein gene

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A large kindred with autosomal dominant Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Alpha-synuclein dysfunction in Lewy body diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Distribution, type, and origin of Parkin mutations: review and case studies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Parkin mutations are frequent in patients with isolated early-onset parkinsonism.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Parkinson's disease in Ireland: clinical presentation and genetic heterogeneity in patients with parkin mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Evaluation of 50 probands with early-onset Parkinson's disease for Parkin mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Parkin disease: a phenotypic study of a large case series

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

How much phenotypic variation can be attributed to parkin genotype?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Olfactory impairment in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Olfaction differentiates parkin disease from early-onset parkinsonism and Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Olfaction and Parkinson's syndromes: its role in differential diagnosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Lewy bodies and parkinsonism in families with parkin mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Significance of the parkin gene and protein in understanding Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical features and neuroimaging of PARK7-linked parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

The role of pathogenic DJ-1 mutations in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Homozygous PINK1 C-terminus mutation causing early-onset parkinsonism.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinicogenetic study of PINK1 mutations in autosomal recessive early-onset parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

PINK1 (PARK6) associated Parkinson disease in Ireland

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

PINK1 mutations are associated with sporadic early-onset parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: an 18F-dopa PET study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

LRRK2 gene in Parkinson disease: Mutation analysis and case control association study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical features of LRRK2-associated Parkinson's disease in central Norway

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

LRRK2 mutations in Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A clinic-based study of the LRRK2 gene in Parkinson disease yields new mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

The phenylalanine loading test in the differential diagnosis of dystonia

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

High mutation rate in dopa-responsive dystonia: detection with comprehensive GCHI screening

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Genetic testing in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Parkinson's disease therapy: tailoring choices for early and late disease, young and old patients

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Alternatives to levodopa in the initial treatment of early Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Progress in clinical neurosciences: a forum on the early management of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Present and future drug treatment for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Pramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Disease modification in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Excessive Daytime Sleepiness and Sudden-Onset Sleep in Parkinson Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Efficacy and safety of entacapone in Parkinson's disease patients with suboptimal levodopa response: a 6-month randomized placebo-controlled double-blind study in Germany and Austria (Celomen study).

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A randomized placebo-controlled trial of rasagiline in levodopa-treated patients with Parkinson disease and motor fluctuations: the PRESTO study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Controlled release levodopa-carbidopa (CR-5) in the management of parkinsonian motor fluctuations.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Amantadine for levodopa-induced dyskinesias: a 1-year follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Apomorphine monotherapy in the treatment of refractory motor complications of Parkinson's disease: long-term follow-up study of 64 patients

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

A 10 year retrospective audit of long-term apomorphine use in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Subthalamic nucleus or internal pallidal stimulation in young onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Non-motor symptoms of Parkinson's disease: diagnosis and management

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Young- versus older-onset Parkinson's disease: impact of disease and psychosocial consequences.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Impact of Parkinson's disease on patients' adolescent and adult children.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Living with a person who has Parkinson's disease: the spouse's perspective by stage of disease. Parkinson's Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Cognitive behavioural therapy (CBT) for carers of patients with Parkinson's disease: a preliminary randomised controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

The effect of pregnancy in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Pregnancy in Parkinson's disease: unique case report and review of the literature

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Quantitative assessment of driving performance in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Driving in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2806%2970411-2

7 January 2021

10.1016/S1474-4422(06)70411-2

Identifiers

DOI

1 reference

14 August 2017

1 reference

PubMed ID

16545752