Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus. (Q36423215)

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18 January 2020

review article

4 references

26 August 2020

1 November 2020

3 November 2020

Targeting Toll-like receptor signaling in plasmacytoid dendritic cells and autoreactive B cells as a therapy for lupus (English)

1 reference

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18 January 2020

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3 November 2020

cell surface receptor

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pattern recognition receptors

31 July 2019

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12 October 2019

hemic and immune systems

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18 October 2019

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26 August 2020

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18 January 2020

author name string

Petar S Lenert

series ordinal

1

1 reference

14 August 2017

10 January 2006

14 references

12 March 2019

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17 June 2019

31 July 2019

3 August 2019

4 August 2019

17 September 2019

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15 December 2019

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18 January 2020

26 August 2020

1 November 2020

3 November 2020

Arthritis Research and Therapy

14 references

12 March 2019

23 March 2019

17 June 2019

31 July 2019

3 August 2019

4 August 2019

17 September 2019

12 October 2019

18 October 2019

15 December 2019

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18 January 2020

26 August 2020

1 November 2020

3 November 2020

8

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18 January 2020

page(s)

203

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18 January 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16542467%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/ar1888

18 January 2020

exact match

0 references

cites work

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30 September 2017

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30 September 2017

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Inherited disorders of human Toll-like receptor signaling: immunological implications.

30 September 2017

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30 September 2017

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Plasmacytoid dendritic cells in immunity

30 September 2017

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30 September 2017

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Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow

30 September 2017

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30 September 2017

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30 September 2017

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CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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DNA methylation and autoimmune disease

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation

30 September 2017

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30 September 2017

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30 September 2017

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Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells

30 September 2017

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30 September 2017

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30 September 2017

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Type-I interferon receptor deficiency reduces lupus-like disease in NZB mice

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

Marginal-zone B cells

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30 September 2017

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30 September 2017

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Autoreactivity by design: innate B and T lymphocytes

30 September 2017

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30 September 2017

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30 September 2017

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Autoreactive B cells in the marginal zone that express dual receptors

30 September 2017

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CpG stimulation of primary mouse B cells is blocked by inhibitory oligodeoxyribonucleotides at a site proximal to NF-kappaB activation

30 September 2017

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Toll-like receptors: critical proteins linking innate and acquired immunity

30 September 2017

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An etiopathogenic role for the type I IFN system in SLE.

30 September 2017

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Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

30 September 2017

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Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells

30 September 2017

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Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.

30 September 2017

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The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

30 September 2017

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Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs

30 September 2017

1 reference

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A Toll-like receptor recognizes bacterial DNA

30 September 2017

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IFN-gamma transgenic mice: clues to the pathogenesis of systemic lupus erythematosus?

30 September 2017

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Inhibition of murine macrophage IL-12 production by natural and synthetic DNA.

30 September 2017

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Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy

30 September 2017

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CpG DNA switches on Th1 immunity and modulates antigen-presenting cell function

30 September 2017

1 reference

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Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

30 September 2017

1 reference

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Molecular mimicry and immune-mediated diseases

30 September 2017

1 reference

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Systemic exposure to irradiated apoptotic cells induces autoantibody production

30 September 2017

1 reference

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Dendritic cells and the control of immunity

30 September 2017

1 reference

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Dendritic cells enhance growth and differentiation of CD40-activated B lymphocytes

30 September 2017

1 reference

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Modulation of renal disease in autoimmune NZB/NZW mice by immunization with bacterial DNA.

30 September 2017

1 reference

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CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

CpG DNA: a pathogenic factor in systemic lupus erythematosus?

30 September 2017

1 reference

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Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

30 September 2017

1 reference

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Genetic and structural evidence for antigen selection of anti-DNA antibodies.

30 September 2017

1 reference

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CpG motifs in bacterial DNA trigger direct B-cell activation

30 September 2017

1 reference

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Deoxybonucleic acid (DNA) and antibodies to DNA in the serum of patients with systemic lupus erythematosus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

CpG DNA rescues B cells from apoptosis by activating NFkappaB and preventing mitochondrial membrane potential disruption via a chloroquine-sensitive pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumour

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Immune Interferon in the Circulation of Patients with Autoimmune Disease

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Toll-like receptor-7 modulates immune complex glomerulonephritis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Human splenic marginal zone B cells lack expression of activation-induced cytidine deaminase.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Induction of systemic lupus erythematosus-like syndrome in syngeneic mice by immunization with activated lymphocyte-derived DNA.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Rapid response of marginal zone B cells to viral particles

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Systemic lupus erythematosus and related autoimmune diseases are antigen-driven, epigenetic diseases.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Cutting edge: expansion and activation of a population of autoreactive marginal zone B cells in a model of estrogen-induced lupus

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB × NZW mice

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1526546

Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity

4 December 2018

1 reference

12 December 2020

The pathogenesis of autoimmunity in New Zealand mice. II. Acceleration of glomerulonephritis by polyinosinic-polycytidylic acid

1 reference

12 December 2020

Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content

1 reference

12 December 2020

Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon

1 reference

12 December 2020

Serum interferon levels in patients with systemic lupus erythematosus

1 reference

12 December 2020

Activation of marginal zone B cells from lupus mice with type A(D) CpG-oligodeoxynucleotides

1 reference

12 December 2020

Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon-α Induction by CpG-A in Plasmacytoid Dendritic Cells

1 reference

12 December 2020

Experimental models of systemic lupus erythematosus: anti-dsDNA in murine lupus

1 reference

12 December 2020

Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone

1 reference

12 December 2020

Differential activation of anti-erythrocyte and anti-DNA autoreactive B lymphocytes by the Yaa mutation

1 reference

12 December 2020

Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus

1 reference

12 December 2020

Autoreactive B cells escape clonal deletion by expressing multiple antigen receptors

1 reference

12 December 2020

Structural characterization of the inhibitory DNA motif for the type A (D)-CpG-induced cytokine secretion and NK-cell lytic activity in mouse spleen cells

1 reference

12 December 2020

Activation of autoreactive B cells by CpG dsDNA

1 reference

12 December 2020

Type I IFN protects against murine lupus

1 reference

12 December 2020

IL-10-producing B220+CD11c- APC in mouse spleen

1 reference

12 December 2020

IFN-alpha/beta enhances BCR-dependent B cell responses

1 reference

12 December 2020

Inhibitory oligonucleotides specifically block effects of stimulatory CpG oligonucleotides in B cells

1 reference

12 December 2020

Type I Interferon controls the onset and severity of autoimmune manifestations in lpr mice

1 reference

12 December 2020

Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

1 reference

12 December 2020

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

1 reference

12 December 2020

In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR1888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16542467%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16542467%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference