DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs (Q36414762)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs (English)

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16 February 2020

0 references

1 reference

3

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16 February 2020

Robert J Schneider

series ordinal

4

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16 February 2020

author name string

Michelle Badura

series ordinal

1

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16 February 2020

Steve Braunstein

series ordinal

2

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16 February 2020

language of work or name

English

0 references

publication date

29 October 2012

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Proceedings of the National Academy of Sciences of the United States of America

16 February 2020

published in

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16 February 2020

volume

109

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16 February 2020

issue

46

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16 February 2020

page(s)

18767-18772

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MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle

16 February 2020

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30 September 2017

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Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae

30 September 2017

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Regulation of protein synthesis by ionizing radiation.

30 September 2017

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Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer.

30 September 2017

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Direct functional interaction of initiation factor eIF4G with type 1 internal ribosomal entry sites

30 September 2017

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Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

30 September 2017

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30 September 2017

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p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

30 September 2017

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DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis

30 September 2017

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eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy

30 September 2017

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DNA-damage repair; the good, the bad, and the ugly

30 September 2017

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30 September 2017

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A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer.

30 September 2017

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DNA damage, cellular senescence and organismal ageing: causal or correlative?

30 September 2017

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Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells

30 September 2017

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Incorporation of an internal ribosome entry site-dependent mechanism in arsenic-induced GADD45alpha expression

30 September 2017

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Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog.

30 September 2017

1 reference

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Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung

30 September 2017

1 reference

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Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

30 September 2017

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GammaH2AX and its role in DNA double-strand break repair

30 September 2017

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HIF-1 and tumour radiosensitivity

30 September 2017

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Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

30 September 2017

1 reference

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Control of mammalian translation by mRNA structure near caps

30 September 2017

1 reference

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Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation

30 September 2017

1 reference

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Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation

30 September 2017

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Gadd45a, a p53- and BRCA1-regulated stress protein, in cellular response to DNA damage

30 September 2017

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ATM signaling and genomic stability in response to DNA damage

30 September 2017

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30 September 2017

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53BP1, a mediator of the DNA damage checkpoint

30 September 2017

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Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45a

30 September 2017

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30 September 2017

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Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation

30 September 2017

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Autophagy as a regulated pathway of cellular degradation

30 September 2017

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Internal ribosome initiation of translation and the control of cell death.

30 September 2017

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A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection

30 September 2017

1 reference

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A new translational regulator with homology to eukaryotic translation initiation factor 4G

30 September 2017

1 reference

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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

Translation eukaryotic initiation factor 4G recognizes a specific structural element within the internal ribosome entry site of encephalomyocarditis virus RNA.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

Cap-independent translation is required for starvation-induced differentiation in yeast

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

A novel eIF4G homolog, Off-schedule, couples translational control to meiosis and differentiation in Drosophila spermatocytes

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

Translation driven by an eIF4G core domain in vivo

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503184

21 September 2018

Identifiers

DOI

10.1073/PNAS.1203853109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23112151%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

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