Transcriptional profiling of peripheral blood cells in clinical pharmacogenomic studies (Q36412663)

14 August 2017

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title

Transcriptional profiling of peripheral blood cells in clinical pharmacogenomic studies (English)

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14 August 2017

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Michael E Burczynski

1

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PubMed ID

16515398

14 August 2017

Andrew J Dorner

series ordinal

2

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14 August 2017

1 March 2006

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14 August 2017

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14 August 2017

7

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14 August 2017

2

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14 August 2017

187-202

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Clinical pharmacogenomics and transcriptional profiling in early phase oncology clinical trials

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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

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Gene expression profiles in human autoimmune disease

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Microarray analysis of gene expression in lupus

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Gene expression signatures for autoimmune disease in peripheral blood mononuclear cells

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Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor

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Gene expression profiling of relevant biomarkers for treatment evaluation in multiple sclerosis

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Gene expression profiling in peripheral blood mononuclear cells from lupus patients with active and inactive disease

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Gene expression in mononuclear cells from patients with inflammatory bowel disease.

21 January 2018

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A gene expression signature for recent onset rheumatoid arthritis in peripheral blood mononuclear cells

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Peripheral blood gene expression profiling in rheumatoid arthritis.

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Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils

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The emerging role of interferon in human systemic lupus erythematosus

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Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

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Chronic myelogenous leukemia molecular signature.

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Pharmacogenomic analysis of cytogenetic response in chronic myeloid leukemia patients treated with imatinib

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Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia

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Prognostically useful gene-expression profiles in acute myeloid leukemia.

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Microarray analysis reveals differences in gene expression of circulating CD8(+) T cells in melanoma patients and healthy donors.

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The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model

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Functional genomic relationships in HIV-1 disease revealed by gene-expression profiling of primary human peripheral blood mononuclear cells.

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Gene expression profiles in peripheral blood mononuclear cells of SARS patients

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Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes

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Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression.

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Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation.

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Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease

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Blood genomic expression profile for neuronal injury

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Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and Down's syndrome

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Blood gene expression profiling of neurologic diseases: a pilot microarray study

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Human blood genomics: distinct profiles for gender, age and neurofibromatosis type 1.

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Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

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Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia

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Peripheral blood mononuclear cell gene expression profiles identify emergent post-traumatic stress disorder among trauma survivors.

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Gene expression in peripheral blood mononuclear cells from patients with chronic fatigue syndrome

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Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects

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Application of transcriptome analysis to clinical pharmacology studies

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Gene-expression profiling of the response of peripheral blood mononuclear cells and melanoma metastases to systemic IL-2 administration

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Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification

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Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer

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Discovery of novel biomarkers by microarray analysis of peripheral blood mononuclear cell gene expression in benzene-exposed workers

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Genomic and proteomic determinants of outcome in patients undergoing thoracoabdominal aortic aneurysm repair

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Transcription-based prediction of response to IFNbeta using supervised computational methods

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Risk factors associated with beta-amyloid(1-42) immunotherapy in preimmunization gene expression patterns of blood cells.

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Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation

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Comparison of different isolation techniques prior gene expression profiling of blood derived cells: impact on physiological responses, on overall expression and the role of different cell types.

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The transcriptome in blood: challenges and solutions for robust expression profiling

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Application of genome-wide expression analysis to human health and disease

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Ex vivo induction of cytokine mRNA expression in human blood samples

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Improvement of molecular monitoring of residual disease in leukemias by bedside RNA stabilization

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Assessment of two methods for handling blood in collection tubes with RNA stabilizing agent for surveillance of gene expression profiles with high density microarrays.

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Optimized blood cell profiling method for genomic biomarker discovery using high-density microarray.

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Forecasting the cytokine storm following systemic interleukin (IL)-2 administration

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Roadmap for developing and validating therapeutically relevant genomic classifiers

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The Economic Implications of Noninvasive Molecular Testing for Cardiac Allograft Rejection

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GENOME-WIDE MONOCYTIC mRNA EXPRESSION IN POLYTRAUMA PATIENTS FOR IDENTIFICATION OF CLINICAL OUTCOME

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Whole blood and leukocyte RNA isolation for gene expression analyses

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21 January 2018

Identifiers

DOI

10.2217/14622416.7.2.187

1 reference

14 August 2017

1 reference

PubMed ID

16515398