Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs (Q36405518)

14 August 2017

Stem Cell-Specific Mechanisms Ensure Genomic Fidelity within HSCs and upon Aging of HSCs (English)

1 reference

14 August 2017

3

1 reference

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9 June 2020

Maria C Florian

4

1 reference

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9 June 2020

Mona Vogel

6

1 reference

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9 June 2020

Michael D Milsom

13

1 reference

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9 June 2020

author name string

Bettina M Moehrle

1

1 reference

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9 June 2020

Kalpana Nattamai

2

1 reference

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9 June 2020

Marnie Ryan

5

1 reference

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9 June 2020

Corinna Bliederhaeuser

7

1 reference

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9 June 2020

Karin Soller

8

1 reference

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9 June 2020

Daniel R Prows

9

1 reference

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9 June 2020

Amir Abdollahi

10

1 reference

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9 June 2020

David Schleimer

11

1 reference

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9 June 2020

Dagmar Walter

12

1 reference

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9 June 2020

Peter Stambrook

14

1 reference

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9 June 2020

Matthew Porteus

15

1 reference

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9 June 2020

Hartmut Geiger

16

1 reference

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9 June 2020

publication date

10 December 2015

1 reference

14 August 2017

1 reference

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9 June 2020

volume

13

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9 June 2020

page(s)

2412-2424

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9 June 2020

issue

11

1 reference

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describes a project that uses

9 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4691560/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

30 September 2017

1 reference

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Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle

30 September 2017

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Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner

30 September 2017

1 reference

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Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.

30 September 2017

1 reference

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Regenerative capacity of old muscle stem cells declines without significant accumulation of DNA damage

30 September 2017

1 reference

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Accumulation of DNA damage-induced chromatin alterations in tissue-specific stem cells: the driving force of aging?

30 September 2017

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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

30 September 2017

1 reference

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The ageing haematopoietic stem cell compartment

30 September 2017

1 reference

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DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions

30 September 2017

1 reference

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Mechanisms that regulate stem cell aging and life span

30 September 2017

1 reference

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Concise review: hematopoietic stem cell aging, life span, and transplantation

30 September 2017

1 reference

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The origin and evolution of mutations in acute myeloid leukemia

30 September 2017

1 reference

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Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

30 September 2017

1 reference

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Distinct regulatory mechanisms and functions for p53-activated and p53-repressed DNA damage response genes in embryonic stem cells

30 September 2017

1 reference

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A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

30 September 2017

1 reference

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Cell cycle regulation in hematopoietic stem cells

30 September 2017

1 reference

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Understanding the limitations of radiation-induced cell cycle checkpoints

30 September 2017

1 reference

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Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging

30 September 2017

1 reference

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Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

30 September 2017

1 reference

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Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.

30 September 2017

1 reference

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Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

30 September 2017

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Genotoxic stress abrogates renewal of melanocyte stem cells by triggering their differentiation

30 September 2017

1 reference

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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

30 September 2017

1 reference

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Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide

30 September 2017

1 reference

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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

30 September 2017

1 reference

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Design and testing of zinc finger nucleases for use in mammalian cells

30 September 2017

1 reference

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Comparison of zinc finger nucleases for use in gene targeting in mammalian cells

30 September 2017

1 reference

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The retinoblastoma tumor suppressor is a critical intrinsic regulator for hematopoietic stem and progenitor cells under stress

30 September 2017

1 reference

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p53 signaling in response to increased DNA damage sensitizes AML1-ETO cells to stress-induced death

30 September 2017

1 reference

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

30 September 2017

1 reference

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Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

30 September 2017

1 reference

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DNA repair is limiting for haematopoietic stem cells during ageing

30 September 2017

1 reference

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Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

30 September 2017

1 reference

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Increased hematopoietic stem cell mobilization in aged mice

30 September 2017

1 reference

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30 September 2017

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Cytokine-based treatment of accidentally irradiated victims and new approaches

30 September 2017

1 reference

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Differential role of RB in response to UV and IR damage

30 September 2017

1 reference

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30 September 2017

1 reference

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Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

30 September 2017

1 reference

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Cell-cycle checkpoints and cancer

30 September 2017

1 reference

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Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

30 September 2017

1 reference

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Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation

30 September 2017

1 reference

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

30 September 2017

1 reference

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30 September 2017

1 reference

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Chimeric nucleases stimulate gene targeting in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Essential role of mouse telomerase in highly proliferative organs

30 September 2017

1 reference

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ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Rapid accumulation of genome rearrangements in liver but not in brain of old mice

30 September 2017

1 reference

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

30 September 2017

1 reference

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Plasmid-based transgenic mouse model for studying in vivo mutations

30 September 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

30 September 2017

1 reference

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Transgenic mouse models for studying mutations in vivo: applications in aging research

28 June 2018

1 reference

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Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Quantification of genomic mutations in murine hematopoietic cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Ex vivo culture rescues hematopoietic stem cells with long-term repopulating capacity following harvest from lethally irradiated mice.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Down-regulation of DNA repair in human CD34(+) progenitor cells corresponds to increased drug sensitivity and apoptotic response

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Age- and stage-specific regulation patterns in the hematopoietic stem cell hierarchy.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691560

Mutagenic potential of temozolomide in bone marrow cells in vivo

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26686632

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2015.11.030

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26686632%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26686632%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference