E47 is required for V(D)J recombinase activity in common lymphoid progenitors (Q36403067)

14 August 2017

E47 is required for V(D)J recombinase activity in common lymphoid progenitors (English)

1 reference

14 August 2017

Lisa Borghesi

1

1 reference

14 August 2017

Jennifer Aites

2

1 reference

14 August 2017

Shakira Nelson

3

1 reference

14 August 2017

Preslav Lefterov

4

1 reference

14 August 2017

Pamela James

5

1 reference

14 August 2017

Rachel Gerstein

6

1 reference

14 August 2017

language of work or name

English

0 references

publication date

1 December 2005

1 reference

Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

202

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14 August 2017

12

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14 August 2017

1669-1677

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Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Contingent gene regulatory networks and B cell fate specification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Regulation of E2A gene expression in B-lymphocyte development

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Developmental separation of V(D)J recombinase expression and initiation of IgH recombination in B lineage progenitors in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Characterization of chromatin structure and enhancer elements for murine recombination activating gene-2.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

RAG2 is regulated differentially in B and T cells by elements 5' of the promoter

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Positive and negative regulation of V(D)J recombination by the E2A proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

The helix-loop-helix gene E2A is required for B cell formation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

A common pathway for dendritic cell and early B cell development.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Both E12 and E47 allow commitment to the B cell lineage

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Assembling a gene regulatory network for specification of the B cell fate

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

A conserved transcriptional enhancer regulates RAG gene expression in developing B cells.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Id3 inhibits B lymphocyte progenitor growth and survival in response to TGF-beta

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Loss of c-kit accompanies B-lineage commitment and acquisition of CD45R by most murine B-lymphocyte precursors.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Rearrangement of IgH genes in normal thymocyte development

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212960

Circulating hematopoietic progenitors with T lineage potential

21 October 2018

1 reference

12 December 2020

Constitutive expression of the Id1 gene impairs mouse B cell development

1 reference

12 December 2020

Identification of the earliest B lineage stage in mouse bone marrow

1 reference

12 December 2020

Coordinate regulation of RAG1 and RAG2 by cell type-specific DNA elements 5' of RAG2

1 reference

12 December 2020

Thymopoiesis independent of common lymphoid progenitors

1 reference

12 December 2020

Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation events

1 reference

12 December 2020

Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20051190

1 reference

14 August 2017

1 reference

14 August 2017

1 reference